Literature DB >> 11261224

[Hepatocellular carcinoma in a patient with hereditary hemochromatosis without cirrhosis].

M Pellisé1, J González-Abraldes, M Navasa, R Miquel, M Bruguera.   

Abstract

Hepatocellular carcinoma in patients with hereditary hemochromatosis in the cirrhotic phase is one of the complications causing greatest mortality and may present in spite of removal of excess iron by bloodletting. Hepatocellular carcinoma is usually considered to occur in cirrhotic livers and consequently measures for the early diagnosis of this complication are only recommended in this type of patient. We present the case of a 69-year-old female patient with non-cirrhotic hemochromatosis who, 6 years after undergoing successful treatment, developed hepatocellular carcinoma. This observation should be added to the 12 cases published in the literature. Criteria should be established for the early diagnosis of hepatocellular carcinoma in patients with hereditary hemochromatosis, irrespective of whether they have cirrhosis.

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Year:  2001        PMID: 11261224     DOI: 10.1016/s0210-5705(01)70139-2

Source DB:  PubMed          Journal:  Gastroenterol Hepatol        ISSN: 0210-5705            Impact factor:   2.102


  3 in total

1.  Protective altruistic phlebotomy: hereditary haemochromatosis presenting as hepatocellular carcinoma in a non-cirrhotic 83-year-old man.

Authors:  Kohtaro Ooka; Ifeyinwa Onyiuke; Xuchen Zhang; Tamar Hamosh Taddei
Journal:  BMJ Case Rep       Date:  2016-09-02

Review 2.  MicroRNAs and liver cancer associated with iron overload: therapeutic targets unravelled.

Authors:  Catherine M Greene; Robert B Varley; Matthew W Lawless
Journal:  World J Gastroenterol       Date:  2013-08-28       Impact factor: 5.742

3.  Hypervascular nodule in a fibrotic liver overloaded with iron: identification of a premalignant area with preserved liver architecture.

Authors:  António Sá Cunha; Jean-Frédéric Blanc; Hervé Trillaud; Victor De Ledinghen; Charles Balabaud; Paulette Bioulac-Sage
Journal:  Comp Hepatol       Date:  2005-05-04
  3 in total

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