Literature DB >> 1126110

Plasma testosterone levels during chronic heroin use and protracted astinence. A study of Hong Kong addicts.

J H Mendelson, N K Mello.   

Abstract

The effects of heroin use and subsequent prolonged abstinence on plasma testosterone levels were examined in 31 male heroin addicts. Heroin (alone and in combination with methadone) significantly suppressed plasma testosterone levels. However, drug-induced testosterone suppression does not appear to be permanent in adult addicts. Recovery of testosterone levels to normal occurred after about one month of heroin abstinence.

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Year:  1975        PMID： 1126110     DOI： 10.1002/cpt1975175529

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


  7 in total

Review 1.  A systematic review of opioid effects on the hypogonadal axis of cancer patients.

Authors:  Kerry McWilliams; Claribel Simmons; Barry J Laird; Marie T Fallon
Journal:  Support Care Cancer       Date:  2014-03-15       Impact factor: 3.603

2.  Mechanisms leading to hypogonadism in men with burns injuries.

Authors:  C G Semple; W R Robertson; R Mitchell; D Gordon; C E Gray; G H Beastall; W H Reid
Journal:  Br Med J (Clin Res Ed)       Date:  1987-08-15

3.  Opioid and cocaine combined effect on cocaine-induced changes in HPA and HPG axes hormones in men.

Authors:  Nathalie V Goletiani; Jack H Mendelson; Michelle B Sholar; Arthur J Siegel; Nancy K Mello
Journal:  Pharmacol Biochem Behav       Date:  2008-09-18       Impact factor: 3.533

4.  Buprenorphine effects on cigarette smoking.

Authors:  N K Mello; S E Lukas; J H Mendelson
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

5.  Pituitary function following treatment with reproductive toxins.

Authors:  R L Cooper; J M Goldman; G L Rehnberg
Journal:  Environ Health Perspect       Date:  1986-12       Impact factor: 9.031

Review 6.  Behavioral sex differences in cocaine and opioid use disorders: The role of gonadal hormones.

Authors:  Melissa C Knouse; Lisa A Briand
Journal:  Neurosci Biobehav Rev       Date:  2021-06-29       Impact factor: 9.052

7.  In the face of threat: neural and endocrine correlates of impaired facial emotion recognition in cocaine dependence.

Authors:  K D Ersche; C C Hagan; D G Smith; P S Jones; A J Calder; G B Williams
Journal:  Transl Psychiatry       Date:  2015-05-26       Impact factor: 6.222
  7 in total

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