| Literature DB >> 11260172 |
B Kirby1, A M Marsland, A J Carmichael, C E Griffiths.
Abstract
Plaques of psoriasis contain increased levels of cytokines, including tumour necrosis factor-alpha (TNF-alpha), which are thought to be essential to the maintenance of the psoriatic process. We report the successful treatment of severe, recalcitrant psoriasis when infliximab (a monoclonal antibody to TNF-alpha) was used in combination with methotrexate.Entities:
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Year: 2001 PMID： 11260172 DOI： 10.1046/j.1365-2230.2001.00753.x
Source DB: PubMed Journal: Clin Exp Dermatol ISSN： 0307-6938 Impact factor: 3.470