Literature DB >> 11259239

Crushed prednisolone tablets or oral solution for acute asthma?

M E Lucas-Bouwman1, R J Roorda, F G Jansman, P L Brand.   

Abstract

In a randomised trial, treatment with prednisolone in two formulations (oral solution or crushed tablets) was compared in 78 young children with acute asthma. Prednisolone oral solution was better tolerated than crushed tablets (less vomiting, superior taste); clinical resolution was similar.

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Year:  2001        PMID： 11259239      PMCID： PMC1718704          DOI： 10.1136/adc.84.4.347

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN： 0003-9888            Impact factor:   3.791


  3 in total

1.  Palatability and cost comparison of five liquid corticosteroid formulations.

Authors:  C J Hutto; T H Bratton
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2.  A clinical scoring system for the diagnosis of respiratory failure. Preliminary report on childhood status asthmaticus.

Authors:  D W Wood; J J Downes; H I Lecks
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3.  Bioavailability assessment of a liquid prednisone preparation.

Authors:  J W Georgitis; K A Flesher; S J Szefler
Journal:  J Allergy Clin Immunol       Date:  1982-10       Impact factor: 10.793
  3 in total
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Review 3.  Management of acute respiratory diseases in the pediatric population: the role of oral corticosteroids.

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4.  Pharmacokinetics of prednisolone in children: an open-label, randomised, two-treatment cross-over trial investigating the bioequivalence of different prednisolone formulations in children with airway disease.

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5.  Oral Dexamethasone vs. Oral Prednisone for Children With Acute Asthma Exacerbations: A Systematic Review and Meta-Analysis.

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6.  Acceptability of Prednisolone in an Open-Label Randomised Cross-Over Study-Focus on Formulation in Children.

Authors:  Sissel Sundell Haslund-Krog; Inger Merete Jørgensen; Kim Dalhoff; Helle Holst
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7.  Single dose oral dexamethasone versus multi-dose prednisolone in the treatment of acute exacerbations of asthma in children who attend the emergency department: study protocol for a randomized controlled trial.

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Review 9.  It's not all about inhaled treatment: challenges with oral therapy in paediatric respiratory medicine.

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  9 in total

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