| Literature DB >> 11257397 |
Abstract
The ability of heat shock proteins to: (a) chaperone peptides, including antigenic peptides; (b) interact with antigen presenting cells through a receptor; (c) stimulate antigen presenting cells to secrete inflammatory cytokines; and (d) mediate maturation of dendritic cells, makes them a one-stop shop for the immune system. These properties also permit the utilization of heat shock proteins for development of a new generation of prophylactic and therapeutic vaccines against cancers and infectious diseases.Entities:
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Year: 2001 PMID： 11257397 DOI： 10.1016/s0264-410x(00)00492-8
Source DB: PubMed Journal: Vaccine ISSN： 0264-410X Impact factor: 3.641