Literature DB >> 11257055

Diversity of Tn1546 elements in clinical isolates of glycopeptide-resistant enterococci from Scottish hospitals.

A R Brown1, A C Townsley, S G Amyes.   

Abstract

The Tn1546-related elements of 48 Van glycopetide-resistant enterococci were compared. Ten distinct Tn1546 types were identified with variation primarily due to IS1542 and IS1216V-like insertions. Clonal isolates frequently differed in their Tn1546 type, indicating instability of Tn1546-related elements. A putative hybrid promoter was identified, generated upstream of vanR by the insertion of IS1542. The presence of this hybrid promoter was associated with constitutive expression of the van genes and elevated teicoplanin resistance.

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Year:  2001        PMID： 11257055      PMCID： PMC90464          DOI： 10.1128/AAC.45.4.1309-1311.2001

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  15 in total

1.  Effects of the movement of insertion sequences on the structure of VanA glycopeptide resistance elements in Enterococcus faecium.

Authors:  A L Darini; M F Palepou; N Woodford
Journal:  Antimicrob Agents Chemother       Date:  2000-05       Impact factor: 5.191

2.  Molecular diversity and evolutionary relationships of Tn1546-like elements in enterococci from humans and animals.

Authors:  R J Willems; J Top; N van den Braak; A van Belkum; D J Mevius; G Hendriks; M van Santen-Verheuvel; J D van Embden
Journal:  Antimicrob Agents Chemother       Date:  1999-03       Impact factor: 5.191

3.  Detection of glycopeptide resistance genotypes and identification to the species level of clinically relevant enterococci by PCR.

Authors:  S Dutka-Malen; S Evers; P Courvalin
Journal:  J Clin Microbiol       Date:  1995-01       Impact factor: 5.948

4.  Investigation by long PCR of the genetic elements mediating VaNa glycopeptide resistance in enterococci from uncooked meat in south Manchester.

Authors:  N Woodford; A P Watson; P R Chadwick
Journal:  Adv Exp Med Biol       Date:  1997       Impact factor: 2.622

5.  Molecular analysis of Tn1546 in Enterococcus faecium isolated from animals and humans.

Authors:  L B Jensen; P Ahrens; L Dons; R N Jones; A M Hammerum; F M Aarestrup
Journal:  J Clin Microbiol       Date:  1998-02       Impact factor: 5.948

Review 6.  Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing.

Authors:  F C Tenover; R D Arbeit; R V Goering; P A Mickelsen; B E Murray; D H Persing; B Swaminathan
Journal:  J Clin Microbiol       Date:  1995-09       Impact factor: 5.948

7.  Identification of chromosomal mobile element conferring high-level vancomycin resistance in Enterococcus faecium.

Authors:  S Handwerger; J Skoble
Journal:  Antimicrob Agents Chemother       Date:  1995-11       Impact factor: 5.191

8.  Quantitative analysis of the metabolism of soluble cytoplasmic peptidoglycan precursors of glycopeptide-resistant enterococci.

Authors:  M Arthur; F Depardieu; P Reynolds; P Courvalin
Journal:  Mol Microbiol       Date:  1996-07       Impact factor: 3.501

9.  Identification of the DNA-binding site for the phosphorylated VanR protein required for vancomycin resistance in Enterococcus faecium.

Authors:  T R Holman; Z Wu; B L Wanner; C T Walsh
Journal:  Biochemistry       Date:  1994-04-19       Impact factor: 3.162

10.  Characterization of Tn1546, a Tn3-related transposon conferring glycopeptide resistance by synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147.

Authors:  M Arthur; C Molinas; F Depardieu; P Courvalin
Journal:  J Bacteriol       Date:  1993-01       Impact factor: 3.490
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  5 in total

1.  Nucleotide sequence of IS1678, an insertion sequence in the vanA cluster of enterococci.

Authors:  Woo Kyung Jung; Soon Keun Hong; Hye Cheong Koo; Nam Hoon Kwon; Yong Ho Park
Journal:  Antimicrob Agents Chemother       Date:  2005-04       Impact factor: 5.191

2.  VanA-type enterococci from humans, animals, and food: species distribution, population structure, Tn1546 typing and location, and virulence determinants.

Authors:  F Biavasco; G Foglia; C Paoletti; G Zandri; G Magi; E Guaglianone; A Sundsfjord; C Pruzzo; G Donelli; B Facinelli
Journal:  Appl Environ Microbiol       Date:  2007-03-09       Impact factor: 4.792

3.  Vancomycin-variable enterococci can give rise to constitutive resistance during antibiotic therapy.

Authors:  Maulik N Thaker; Lindsay Kalan; Nicholas Waglechner; Alireza Eshaghi; Samir N Patel; Susan Poutanen; Barbara Willey; Bryan Coburn; Allison McGeer; Donald E Low; Gerard D Wright
Journal:  Antimicrob Agents Chemother       Date:  2014-12-15       Impact factor: 5.191

4.  Genetic rearrangements of TN1546-like elements in vancomycin-resistant Enterococcus faecium isolates collected from hospitalized patients over a seven-year period.

Authors:  Il Joong Park; Wee Gyo Lee; Young Ae Lim; Sung Ran Cho
Journal:  J Clin Microbiol       Date:  2007-09-26       Impact factor: 5.948

5.  Distribution of insertion sequences associated with Tn1546-like elements among Enterococcus faecium isolates from patients in Korea.

Authors:  Ji Young Huh; Wee Gyo Lee; Kyungwon Lee; Wan Shik Shin; Jin Hong Yoo
Journal:  J Clin Microbiol       Date:  2004-05       Impact factor: 5.948
  5 in total

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