| Literature DB >> 11257047 |
W C Ko1, H C Lee, Y C Chuang, S H Ten, C Y Su, J J Wu.
Abstract
The activities of cefotaxime and minocycline against Aeromonas hydrophila were investigated. Cefotaxime (4 times the MIC) plus minocycline (0.75 times the MIC) elicited an inhibitory effect for 48 h in a time-kill study, and more infected mice treated with both drugs survived (91%) than survived after treatment with cefotaxime (9%) or minocycline (44%) alone, suggesting that cefotaxime and minocycline act synergistically against A. hydrophila.Entities:
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Year: 2001 PMID: 11257047 PMCID: PMC90456 DOI: 10.1128/AAC.45.4.1281-1283.2001
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191