| Literature DB >> 11256884 |
A Trautmann1, M Akdis, K Blaser, C A Akdis.
Abstract
Atopic dermatitis is a chronic inflammatory skin disease with a complex immune dysregulation and interplay of genetic, environmental and psychological factors. Activation and skin-selective homing of peripherial-blood T cells, and effector functions in the skin, represent sequential events in the pathogenesis. Dysregulated apoptosis in skin-homing T cells, eosinophils and keratinocytes contributes to the elicitation and persistence of atopic derrmatitis.Entities:
Mesh:
Year: 2000 PMID: 11256884 DOI: 10.1023/a:1009620329213
Source DB: PubMed Journal: Apoptosis ISSN: 1360-8185 Impact factor: 4.677