Literature DB >> 11255928

Deconstructing relative reinforcing efficacy and situating the measures of pharmacological reinforcement with behavioral economics: a theoretical proposal.

W K Bickel1, L A Marsch, M E Carroll.   

Abstract

BACKGROUND: Relative reinforcing efficacy has been assumed to be a homogeneous phenomenon referring to the behavior-strengthening or behavior-maintaining effects of a drug reinforcer. However, a variety of studies suggest that relative reinforcing efficacy may be heterogeneous.
OBJECTIVES: The purpose of this theoretical proposal is to examine the difficulties associated with this conception of reinforcing efficacy and to explore whether relative reinforcing efficacy is a homogenous concept or whether it is composed of several functionally related heterogeneous phenomena. In examining this issue, we explore whether behavioral economic theory may address some of the challenges to the current conception of relative reinforcing efficacy and use this theory to suggest how the differing measures of reinforcing efficacy may relate to one another.
RESULTS: Results indicate that peak-response rate and breakpoint are related to the economic measure of maximal output and elasticity of demand, respectively. Preference is related to and predicted by the relative location of the demand curves obtained under single schedule conditions. This behavioral economic analysis may provide a theoretical understanding of reinforcement that can reconcile results of studies that both support and fail to support the notion of reinforcing efficacy as a homogenous phenomenon.
CONCLUSIONS: If this theoretical proposal is validated by additional studies, then like other natural phenomena found to be heterogeneous, the study of drug reinforcers may require the adoption of several new scientific terms, such as those used in behavioral economics, each of which has analytical precision and refers to homogeneous phenomena.

Mesh:

Year:  2000        PMID: 11255928     DOI: 10.1007/s002130000589

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN: 0033-3158            Impact factor:   4.530


  122 in total

1.  Relative reinforcing effects of different oral ethanol doses in rhesus monkeys.

Authors:  Robert B Stewart; Nian-Sheng Wang; April A Bass; Richard A Meisch
Journal:  J Exp Anal Behav       Date:  2002-01       Impact factor: 2.468

2.  Effects of experimental Unemployment, Employment and Punishment analogs on opioid seeking and consumption in heroin-dependent volunteers.

Authors:  Mark K Greenwald
Journal:  Drug Alcohol Depend       Date:  2010-05-26       Impact factor: 4.492

3.  Effects of economy type and nicotine on the essential value of food in rats.

Authors:  Rachel N Cassidy; Jesse Dallery
Journal:  J Exp Anal Behav       Date:  2012-03       Impact factor: 2.468

4.  Behavioral economic analysis of withdrawal- and cue-elicited craving for tobacco: an initial investigation.

Authors:  James MacKillop; Courtney L Brown; Monika K Stojek; Cara M Murphy; Lawrence Sweet; Ray S Niaura
Journal:  Nicotine Tob Res       Date:  2012-03-13       Impact factor: 4.244

5.  Human behavioral pharmacology, past, present, and future: symposium presented at the 50th annual meeting of the Behavioral Pharmacology Society.

Authors:  Sandra D Comer; Warren K Bickel; Richard Yi; Harriet de Wit; Stephen T Higgins; Galen R Wenger; Chris-Ellyn Johanson; Mary Jeanne Kreek
Journal:  Behav Pharmacol       Date:  2010-07       Impact factor: 2.293

6.  Latent factor structure of a behavioral economic cigarette demand curve in adolescent smokers.

Authors:  L Cinnamon Bidwell; James MacKillop; James G Murphy; Jennifer W Tidey; Suzanne M Colby
Journal:  Addict Behav       Date:  2012-06-13       Impact factor: 3.913

7.  Comparing participant estimated demand intensity on the cigarette Purchase Task to consumption when usual-brand cigarettes were provided free.

Authors:  Tyler D Nighbor; Anthony J Barrows; Janice Y Bunn; Michael J DeSarno; Anthony C Oliver; Sulamunn R M Coleman; Danielle R Davis; Joanna M Streck; Ellaina N Reed; Derek D Reed; Stephen T Higgins
Journal:  Prev Med       Date:  2020-07-24       Impact factor: 4.018

Review 8.  The behavioral pharmacology of effort-related choice behavior: dopamine, adenosine and beyond.

Authors:  John D Salamone; Merce Correa; Eric J Nunes; Patrick A Randall; Marta Pardo
Journal:  J Exp Anal Behav       Date:  2012-01       Impact factor: 2.468

9.  Reduced sensitivity to reward in CB1 knockout mice.

Authors:  Carles Sanchis-Segura; Brandon H Cline; Giovanni Marsicano; Beat Lutz; Rainer Spanagel
Journal:  Psychopharmacology (Berl)       Date:  2004-04-09       Impact factor: 4.530

10.  Sex differences and the role of dopamine receptors in the reward-enhancing effects of nicotine and bupropion.

Authors:  Scott T Barrett; Trevor N Geary; Amy N Steiner; Rick A Bevins
Journal:  Psychopharmacology (Berl)       Date:  2016-10-01       Impact factor: 4.530

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.