| Literature DB >> 11253365 |
C Bustamante1, J C Macosko, G J Wuite.
Abstract
Methods for manipulating single molecules are yielding new information about both the forces that hold biomolecules together and the mechanics of molecular motors. We describe here the physical principles behind these methods, and discuss their capabilities and current limitations.Mesh:
Substances:
Year: 2000 PMID: 11253365 DOI: 10.1038/35040072
Source DB: PubMed Journal: Nat Rev Mol Cell Biol ISSN: 1471-0072 Impact factor: 94.444