Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Ancient origin of the Hox gene cluster.

Literature DB >> 11253066

Ancient origin of the Hox gene cluster.

Abstract

The Hox gene cluster has a crucial function in body patterning during animal development. How and when this gene cluster originated is being clarified by recent data from Cnidaria, a basal animal phylum. The characterization of Hox-like genes from Hydra, sea anemones and jellyfish has revealed that a Hox gene cluster is extremely ancient, having originated even before the divergence of these basal animals.

Entities: Disease

Mesh：

Year: 2001 PMID： 11253066 DOI： 10.1038/35047605

Source DB: PubMed Journal: Nat Rev Genet ISSN： 1471-0056 Impact factor: 53.242

Keyword Cloud
Cited

55 in total

1. Molecular evolution of the homeodomain family of transcription factors.

Authors: S Banerjee-Basu; A D Baxevanis
Journal: Nucleic Acids Res Date: 2001-08-01 Impact factor: 16.971

2. Large-scale protein annotation through gene ontology.

Authors: Hanqing Xie; Alon Wasserman; Zurit Levine; Amit Novik; Vladimir Grebinskiy; Avi Shoshan; Liat Mintz
Journal: Genome Res Date: 2002-05 Impact factor: 9.043

3. Transcriptional repression of peri-implantation EMX2 expression in mammalian reproduction by HOXA10.

Authors: Patrick J Troy; Gaurang S Daftary; Catherine N Bagot; Hugh S Taylor
Journal: Mol Cell Biol Date: 2003-01 Impact factor: 4.272

4. Phylogenetic analysis of vertebrate fibrillar collagen locates the position of zebrafish alpha3(I) and suggests an evolutionary link between collagen alpha chains and hox clusters.

Authors: Ghislaine Morvan-Dubois; Dominique Le Guellec; Robert Garrone; Louise Zylberberg; Laure Bonnaud
Journal: J Mol Evol Date: 2003-11 Impact factor: 2.395

Review 5. Major transitions in evolution by genome fusions: from prokaryotes to eukaryotes, metazoans, bilaterians and vertebrates.

Authors: Jürg Spring
Journal: J Struct Funct Genomics Date: 2003

Review 10. More genes in vertebrates?

Authors: Peter W H Holland
Journal: J Struct Funct Genomics Date: 2003

Ancient origin of the Hox gene cluster.

1. Molecular evolution of the homeodomain family of transcription factors.

2. Large-scale protein annotation through gene ontology.

3. Transcriptional repression of peri-implantation EMX2 expression in mammalian reproduction by HOXA10.

4. Phylogenetic analysis of vertebrate fibrillar collagen locates the position of zebrafish alpha3(I) and suggests an evolutionary link between collagen alpha chains and hox clusters.

Review 5. Major transitions in evolution by genome fusions: from prokaryotes to eukaryotes, metazoans, bilaterians and vertebrates.

6. The phylotypic stage as a boundary of modular memory: non mechanistic perspective.

Review 7. Cis-regulatory RNA elements that regulate specialized ribosome activity.

8. Sexual reproduction reshapes the genetic architecture of digital organisms.

Review 9. Hox genes and their candidate downstream targets in the developing central nervous system.

Review 10. More genes in vertebrates?