| Literature DB >> 11252955 |
T P Stossel1, J Condeelis, L Cooley, J H Hartwig, A Noegel, M Schleicher, S S Shapiro.
Abstract
Filamins are large actin-binding proteins that stabilize delicate three-dimensional actin webs and link them to cellular membranes. They integrate cellular architectural and signalling functions and are essential for fetal development and cell locomotion. Here, we describe the history, structure and function of this group of proteins.Mesh：
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Year: 2001 PMID： 11252955 DOI： 10.1038/35052082
Source DB: PubMed Journal: Nat Rev Mol Cell Biol ISSN： 1471-0072 Impact factor: 94.444