| Literature DB >> 11252007 |
J Halpern1, B W Brown, J Hornberger.
Abstract
Using decision theory, what is an appropriate sample size for a clinical trial, with a binary endpoint? We present a program, suitable for actual planning, which, with some extensions, implements Canner's solution to this question. Examples with a discussion are given. Implications of a Bayesian approach are discussed. Bayesian and Neyman--Pearson approaches are compared. Copyright 2001 John Wiley & Sons, Ltd.Mesh:
Substances:
Year: 2001 PMID: 11252007 DOI: 10.1002/sim.703
Source DB: PubMed Journal: Stat Med ISSN: 0277-6715 Impact factor: 2.373