Literature DB >> 11251298

TNF-alpha and IL-12: a balancing act in macrophage functioning.

X Ma1.   

Abstract

Tumor necrosis factor alpha (TNF-alpha) and interleukin 12 (IL-12) are two major macrophage-derived mediators of inflammatory responses in mammals. Increasing evidence suggests that TNF-alpha is a double-edged sword with both proinflammatory and anti-inflammatory propensities. This article discusses the inter-regulation of TNF-alpha and IL-12 and the impact on the function of macrophages in innate and adaptive immunity.

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Year:  2001        PMID： 11251298     DOI： 10.1016/s1286-4579(00)01359-9

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  31 in total

1.  Clinical, serologic and magnetic resonance imaging of 3 cases of inflammatory myopathy with abundant macrophages in the Japanese population.

Authors:  Shintaro Hara; Tomoko Henmi; Atsushi Kawakami; Keita Fujikawa; Hiroshi Mukae; Yuji Ishimatsu; Noriho Sakamoto; Tomoyuki Kakugawa; Kenzou Kaji; Manabu Fujimoto; Masataka Kuwana; Toshiaki Tsukada; Katsuya Satoh; Masakatsu Motomura; Mami Tamai; Hideki Nakamura; Hiroaki Ida; Tomayoshi Hayashi; Tomoki Origuchi; Katsumi Eguchi; Shigeru Kohno
Journal:  Rheumatol Int       Date:  2010-12-02       Impact factor: 2.631

2.  Intracellular cytokines in peripheral blood leucocytes in children with chronic renal failure.

Authors:  Judi Nairn; Greg Hodge; Paul Henning
Journal:  Pediatr Nephrol       Date:  2005-12-17       Impact factor: 3.714

3.  Cytokine, chemokine and BDNF levels in medication-free pediatric patients with obsessive-compulsive disorder.

Authors:  Rukiye Çolak Sivri; Ayhan Bilgiç; İbrahim Kılınç
Journal:  Eur Child Adolesc Psychiatry       Date:  2018-01-04       Impact factor: 4.785

4.  Acanthamoeba Activates Macrophages Predominantly through Toll-Like Receptor 4- and MyD88-Dependent Mechanisms To Induce Interleukin-12 (IL-12) and IL-6.

Authors:  Antonella Cano; Antonella Mattana; Stuart Woods; Fiona L Henriquez; James Alexander; Craig W Roberts
Journal:  Infect Immun       Date:  2017-05-23       Impact factor: 3.441

5.  Host genetic determinants of the gut microbiota of wild mice.

Authors:  Taichi A Suzuki; Megan Phifer-Rixey; Katya L Mack; Michael J Sheehan; Dana Lin; Ke Bi; Michael W Nachman
Journal:  Mol Ecol       Date:  2019-06-11       Impact factor: 6.185

6.  Effect of chelerythrine against endotoxic shock in mice and its modulation of inflammatory mediators in peritoneal macrophages through the modulation of mitogen-activated protein kinase (MAPK) pathway.

Authors:  Weifeng Li; Ting Fan; Yanmin Zhang; Xiaofeng Niu; Wei Xing
Journal:  Inflammation       Date:  2012-12       Impact factor: 4.092

7.  Protective effects of chelerythrine against lipopolysaccharide-induced endotoxic shock in mice.

Authors:  Xiaofeng Niu; Qingli Mu; Weifeng Li; Huimin Huang; Huan Yao; Huani Li
Journal:  Inflammation       Date:  2014-12       Impact factor: 4.092

8.  Pulmonary Delivery of Nanoparticle-Bound Toll-like Receptor 9 Agonist for the Treatment of Metastatic Lung Cancer.

Authors:  Jillian L Perry; Shaomin Tian; Nisitha Sengottuvel; Emily B Harrison; Balachandra K Gorentla; Chintan H Kapadia; Ning Cheng; J Christopher Luft; Jenny P-Y Ting; Joseph M DeSimone; Chad V Pecot
Journal:  ACS Nano       Date:  2020-06-02       Impact factor: 15.881

9.  A locus on mouse chromosome 6 that determines resistance to herpes simplex virus also influences reactivation, while an unlinked locus augments resistance of female mice.

Authors:  Patric Lundberg; Paula Welander; Harry Openshaw; Christina Nalbandian; Carl Edwards; Lyle Moldawer; Edouard Cantin
Journal:  J Virol       Date:  2003-11       Impact factor: 5.103

10.  Escherichia coli and Staphylococcus aureus elicit differential innate immune responses following intramammary infection.

Authors:  Douglas D Bannerman; Max J Paape; Jai-Wei Lee; Xin Zhao; Jayne C Hope; Pascal Rainard
Journal:  Clin Diagn Lab Immunol       Date:  2004-05
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