Literature DB >> 1125112

Complete heart block as a consequence of atriondal discontinuity.

L M Gerlis, R H Anderson, A E Becker.   

Abstract

We have recently studied a case of complete heart block in which there was considerable difficulty in deciding whether it was of congenital or acquired origin. This was because the heart block was first discovered at the age of 2 years in the course of acute diphtheria. Though diphtheritic infections are known to affect the cardiac conduction system, authenticated cases of post-diphtheritic block persisting after the infection are rare, and, furthermore, histopathological study in this case revealed discontinuity between the atrial tissues and the more peripheral parts of the atrioventricular conduction tissues. This has been more commonly observed in congenital cases of complete heart block and it has been postulated on theoretical grounds that this could be thebasis for congenital heart block; on the other hand, it has been noted in a single casethought to be of acquired origin. Review of the evidence available failed to allow accurate classification of the case into either congenital or acquired categories. Thenormal, segmental development of the atrioventricular node, each segment being of different embryological origin, is discussed and the case presented is understandable in thelight of this.

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Year:  1975        PMID: 1125112      PMCID: PMC483876          DOI: 10.1136/hrt.37.4.345

Source DB:  PubMed          Journal:  Br Heart J        ISSN: 0007-0769


  17 in total

1.  PATHOLOGY OF THE CARDIAC CONDUCTION SYSTEM IN A CASE OF DIPHTHERIA ASSOCIATED WITH ATRIAL ARRHYTHMIAS AND HEART BLOCK.

Authors:  T N JAMES; E W REYNOLDS
Journal:  Circulation       Date:  1963-08       Impact factor: 29.690

2.  Morphology of the human atrioventricular node, with remarks pertinent to its electrophysiology.

Authors:  T N JAMES
Journal:  Am Heart J       Date:  1961-12       Impact factor: 4.749

3.  The development of the sinoventricular conduction system.

Authors:  B M PATTEN
Journal:  Med Bull (Ann Arbor)       Date:  1956-01

Review 4.  A new electrocardiographic concept: synchronized sinoventricular conduction.

Authors:  L Sherf; T N James
Journal:  Dis Chest       Date:  1969-02

5.  D-bulboventricular loop with L-transposition in situs inversus.

Authors:  R H Anderson; R Arnold; R S Jones
Journal:  Circulation       Date:  1972-07       Impact factor: 29.690

6.  The anatomic atrial connections btween sinu and A-V node.

Authors:  J Merideth; J L Titus
Journal:  Circulation       Date:  1968-04       Impact factor: 29.690

7.  Cardiac conduction system: fetal and postnatal development.

Authors:  T N James
Journal:  Am J Cardiol       Date:  1970-02       Impact factor: 2.778

8.  Lack of connection between the atria and the more peripheral conduction system in congenital atrioventricular block.

Authors:  M Lev; J Silverman; F M Fitzmaurice; M H Paul; D E Cassels; R A Miller
Journal:  Am J Cardiol       Date:  1971-05       Impact factor: 2.778

9.  The cellular architecture of the human atrioventricular node, with a note on its morphology in the presence of a left superior vena cava.

Authors:  R H Anderson; R A Latham
Journal:  J Anat       Date:  1971-09       Impact factor: 2.610

10.  Complete atrioventricular block associated with atrial septal defect of the fossa ovalis (secundum) type. A histopathologic study of the conduction systems.

Authors:  M Lev; M H Paul; D E Cassels
Journal:  Am J Cardiol       Date:  1967-02       Impact factor: 2.778

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