Literature DB >> 11250164

Replication checkpoint: preventing mitotic catastrophe.

C E Canman1.   

Abstract

A conserved network of signal transduction pathways prevents mitosis if DNA is damaged or its synthesis incomplete. Loss of this checkpoint control is detrimental to the developing embryo. Recent studies have shed new light on how the essential ATR and Chk1 protein kinases cooperate to prevent such a crisis.

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Year:  2001        PMID: 11250164     DOI: 10.1016/s0960-9822(01)00057-4

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  24 in total

1.  The role of MutY homolog (Myh1) in controlling the histone deacetylase Hst4 in the fission yeast Schizosaccharomyces pombe.

Authors:  Dau-Yin Chang; Guoli Shi; Mickaël Durand-Dubief; Karl Ekwall; A-Lien Lu
Journal:  J Mol Biol       Date:  2010-11-24       Impact factor: 5.469

2.  Targeting DNA Damage Response in Prostate Cancer by Inhibiting Androgen Receptor-CDC6-ATR-Chk1 Signaling.

Authors:  Styliani Karanika; Theodoros Karantanos; Likun Li; Jianxiang Wang; Sanghee Park; Guang Yang; Xuemei Zuo; Jian H Song; Sankar N Maity; Ganiraju C Manyam; Bradley Broom; Ana M Aparicio; Gary E Gallick; Patricia Troncoso; Paul G Corn; Nora Navone; Wei Zhang; Shuhua Li; Timothy C Thompson
Journal:  Cell Rep       Date:  2017-02-21       Impact factor: 9.423

3.  A vertebrate gene, ticrr, is an essential checkpoint and replication regulator.

Authors:  Christopher L Sansam; Nelly M Cruz; Paul S Danielian; Adam Amsterdam; Melissa L Lau; Nancy Hopkins; Jacqueline A Lees
Journal:  Genes Dev       Date:  2010-01-15       Impact factor: 11.361

4.  Enhanced induction of apoptosis in a radio-resistant bladder tumor cell line by combined treatments with X-rays and wortmannin.

Authors:  Trinidad Ortiz; Miguel Angel Burguillos; Guillermo López-Lluch; Plácido Navas; Miguel Herrador; Isabel González; Joaquín Piñero
Journal:  Radiat Environ Biophys       Date:  2008-09-12       Impact factor: 1.925

5.  G(1)/S and G(2)/M cyclin-dependent kinase activities commit cells to death in the absence of the S-phase checkpoint.

Authors:  Nicola Manfrini; Elisa Gobbini; Veronica Baldo; Camilla Trovesi; Giovanna Lucchini; Maria Pia Longhese
Journal:  Mol Cell Biol       Date:  2012-10-08       Impact factor: 4.272

6.  Translation regulatory factor RBM3 is a proto-oncogene that prevents mitotic catastrophe.

Authors:  S M Sureban; S Ramalingam; G Natarajan; R May; D Subramaniam; K S Bishnupuri; A R Morrison; B K Dieckgraefe; D J Brackett; R G Postier; C W Houchen; S Anant
Journal:  Oncogene       Date:  2008-04-21       Impact factor: 9.867

7.  ATR mutation in endometrioid endometrial cancer is associated with poor clinical outcomes.

Authors:  Israel Zighelboim; Amy P Schmidt; Feng Gao; Premal H Thaker; Matthew A Powell; Janet S Rader; Randall K Gibb; David G Mutch; Paul J Goodfellow
Journal:  J Clin Oncol       Date:  2009-05-26       Impact factor: 44.544

8.  Chk1 is activated transiently and targets Cdc25A for degradation at the Xenopus midblastula transition.

Authors:  Ken Shimuta; Nobushige Nakajo; Katsuhiro Uto; Yoshimasa Hayano; Kenji Okazaki; Noriyuki Sagata
Journal:  EMBO J       Date:  2002-07-15       Impact factor: 11.598

9.  Direct role for the replication protein treslin (Ticrr) in the ATR kinase-mediated checkpoint response.

Authors:  Bachar H Hassan; Laura A Lindsey-Boltz; Michael G Kemp; Aziz Sancar
Journal:  J Biol Chem       Date:  2013-05-21       Impact factor: 5.157

10.  Spc24 and Stu2 promote spindle integrity when DNA replication is stalled.

Authors:  Lina Ma; Jennifer McQueen; Lara Cuschieri; Jackie Vogel; Vivien Measday
Journal:  Mol Biol Cell       Date:  2007-05-16       Impact factor: 4.138

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