Literature DB >> 11249129

Synthesis of sulfoquinovosylacylglycerols, inhibitors of eukaryotic DNA polymerase alpha and beta.

S Hanashima1, Y Mizushina, T Yamazaki, K Ohta, S Takahashi, H Sahara, K Sakaguchi, F Sugawar.   

Abstract

Sulfoquinovosyldiacylglycerols (SQDGs) and sulfoquinovosylmonoacylglycerols (SQMGs), bearing diverse fatty acids, were synthesized from D-glucose, and were examined for enzymatic inhibitions of DNA polymerase alpha and beta. These results indicated that the carbon numbers of the fatty acids were highly related to the activities, at least in vitro, of eukaryotic DNA polymerase inhibition.

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Year:  2001        PMID： 11249129     DOI： 10.1016/s0968-0896(00)00252-2

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  15 in total

Review 1.  Targeting DNA polymerase ß for therapeutic intervention.

Authors:  Eva M Goellner; David Svilar; Karen H Almeida; Robert W Sobol
Journal:  Curr Mol Pharmacol       Date:  2012-01       Impact factor: 3.339

2.  A sulphoquinovosyl diacylglycerol is a DNA polymerase epsilon inhibitor.

Authors:  Yoshiyuki Mizushina; Xianai Xu; Hitomi Asahara; Ryo Takeuchi; Masahiko Oshige; Noriko Shimazaki; Masaharu Takemura; Toyofumi Yamaguchi; Kazufumi Kuroda; Stuart Linn; Hiromi Yoshida; Osamu Koiwai; Mineo Saneyoshi; Fumio Sugawara; Kengo Sakaguchi
Journal:  Biochem J       Date:  2003-02-15       Impact factor: 3.857

3.  Evaluation of ion activation strategies and mechanisms for the gas-phase fragmentation of sulfoquinovosyldiacylglycerol lipids from Rhodobacter sphaeroides.

Authors:  Xi Zhang; Cassie J Fhaner; Shelagh M Ferguson-Miller; Gavin E Reid
Journal:  Int J Mass Spectrom       Date:  2012-04-15       Impact factor: 1.986

4.  Inhibition of telomerase by linear-chain fatty acids: a structural analysis.

Authors:  Masako Oda; Takamasa Ueno; Nobuyuki Kasai; Hirotada Takahashi; Hiromi Yoshida; Fumio Sugawara; Kengo Sakaguchi; Hideya Hayashi; Yoshiyuki Mizushina
Journal:  Biochem J       Date:  2002-10-15       Impact factor: 3.857

5.  Inhibitory action of emulsified sulfoquinovosyl acylglycerol on mammalian DNA polymerases.

Authors:  Yoshiyuki Mizushina; Naoki Maeda; Miho Kawasaki; Hideki Ichikawa; Chikako Murakami; Masaharu Takemura; Xianai Xu; Fumio Sugawara; Yoshinobu Fukumori; Hiromi Yoshida; Kengo Sakaguchi
Journal:  Lipids       Date:  2003-10       Impact factor: 1.880

6.  A Multimodal Molecular Imaging Study Evaluates Pharmacological Alteration of the Tumor Microenvironment to Improve Radiation Response.

Authors:  Yoichi Takakusagi; Sarwat Naz; Kaori Takakusagi; Masahiro Ishima; Hiroshi Murata; Keisuke Ohta; Masahiko Miura; Fumio Sugawara; Kengo Sakaguchi; Shun Kishimoto; Jeeva P Munasinghe; James B Mitchell; Murali C Krishna
Journal:  Cancer Res       Date:  2018-10-09       Impact factor: 12.701

7.  An emulsion of sulfoquinovosylacylglycerol with long-chain alkanes increases its permeability to tumor cells.

Authors:  Satoko Aoki; Keisuke Ohta; Kenjiro Matsumoto; Hideki Sakai; Masahiko Abe; Masahiko Miura; Fumio Sugawara; Kengo Sakaguchi
Journal:  J Membr Biol       Date:  2007-03-08       Impact factor: 1.843

Review 8.  Glycolipids from seaweeds and their potential biotechnological applications.

Authors:  Erwan Plouguerné; Bernardo A P da Gama; Renato C Pereira; Eliana Barreto-Bergter
Journal:  Front Cell Infect Microbiol       Date:  2014-12-17       Impact factor: 5.293

9.  Natural Products from Microalgae with Potential against Alzheimer's Disease: Sulfolipids Are Potent Glutaminyl Cyclase Inhibitors.

Authors:  Stephanie Hielscher-Michael; Carola Griehl; Mirko Buchholz; Hans-Ulrich Demuth; Norbert Arnold; Ludger A Wessjohann
Journal:  Mar Drugs       Date:  2016-11-02       Impact factor: 5.118

Review 10.  Total synthesis and structure-activity relationship of glycoglycerolipids from marine organisms.

Authors:  Jun Zhang; Chunxia Li; Guangli Yu; Huashi Guan
Journal:  Mar Drugs       Date:  2014-06-18       Impact factor: 5.118
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