S Reilly1, H Cass. 1. Faculty of Health Sciences, La Trobe University and the Royal Children's Hospital, Melbourne, Australia. s.reilly@latrobe.edu.au
Abstract
PURPOSE/ METHOD: In this paper we review the existing literature on factors that contribute to growth failure in Rett syndrome (RS) with particular emphasis on the extent and nature of the feeding difficulties that arise. Data on growth and feeding related problems, collected over four years in a specialized clinic for females with Rett syndrome are presented and management protocols developed in the clinic discussed. RESULTS/ CONCLUSION: Feeding related problems and growth failure occur commonly in Rett syndrome yet our understanding of the mechanisms causing growth failure are poorly understood. Both nutritional and non-nutritional factors are thought to contribute and it has not been possible to develop efficacious intervention strategies. Consequently, clinical management of growth failure in Rett syndrome is not evidence based.
PURPOSE/ METHOD: In this paper we review the existing literature on factors that contribute to growth failure in Rett syndrome (RS) with particular emphasis on the extent and nature of the feeding difficulties that arise. Data on growth and feeding related problems, collected over four years in a specialized clinic for females with Rett syndrome are presented and management protocols developed in the clinic discussed. RESULTS/ CONCLUSION: Feeding related problems and growth failure occur commonly in Rett syndrome yet our understanding of the mechanisms causing growth failure are poorly understood. Both nutritional and non-nutritional factors are thought to contribute and it has not been possible to develop efficacious intervention strategies. Consequently, clinical management of growth failure in Rett syndrome is not evidence based.
Authors: Nicky S J Halbach; Eric E J Smeets; Jörgen Bierau; Irene M L W Keularts; Guy Plasqui; Peter O O Julu; Ingegerd Witt Engerström; Jaap A Bakker; Leopold M G Curfs Journal: JIMD Rep Date: 2011-09-28
Authors: Amanda L Jefferson; Helen J Woodhead; Sue Fyfe; Julie Briody; Ami Bebbington; Boyd J Strauss; Peter Jacoby; Helen Leonard Journal: Pediatr Res Date: 2011-04 Impact factor: 3.756
Authors: Daniel Charles Tarquinio; Kathleen J Motil; Wei Hou; Hye-Seung Lee; Daniel G Glaze; Steven A Skinner; Jeff L Neul; Fran Annese; Lauren McNair; Judy O Barrish; Suzanne P Geerts; Jane B Lane; Alan K Percy Journal: Neurology Date: 2012-10-03 Impact factor: 9.910
Authors: Kathleen J Motil; Erwin Caeg; Judy O Barrish; Suzanne Geerts; Jane B Lane; Alan K Percy; Fran Annese; Lauren McNair; Steven A Skinner; Hye-Seung Lee; Jeffrey L Neul; Daniel G Glaze Journal: J Pediatr Gastroenterol Nutr Date: 2012-09 Impact factor: 2.839
Authors: Jenny Downs; Kingsley Wong; Madhur Ravikumara; Carolyn Ellaway; Elizabeth J Elliott; John Christodoulou; Peter Jacoby; Helen Leonard Journal: Medicine (Baltimore) Date: 2014-12 Impact factor: 1.889
Authors: Friederike Ehrhart; Susan L M Coort; Elisa Cirillo; Eric Smeets; Chris T Evelo; Leopold M G Curfs Journal: Orphanet J Rare Dis Date: 2016-11-25 Impact factor: 4.123
Authors: Amanda Jefferson; Helen Leonard; Aris Siafarikas; Helen Woodhead; Sue Fyfe; Leanne M Ward; Craig Munns; Kathleen Motil; Daniel Tarquinio; Jay R Shapiro; Torkel Brismar; Bruria Ben-Zeev; Anne-Marie Bisgaard; Giangennaro Coppola; Carolyn Ellaway; Michael Freilinger; Suzanne Geerts; Peter Humphreys; Mary Jones; Jane Lane; Gunilla Larsson; Meir Lotan; Alan Percy; Mercedes Pineda; Steven Skinner; Birgit Syhler; Sue Thompson; Batia Weiss; Ingegerd Witt Engerström; Jenny Downs Journal: PLoS One Date: 2016-02-05 Impact factor: 3.240