X Zhou1, P Li, X Ji. 1. Beijing Hospital, Beijing 100730.
Abstract
OBJECTIVE: To investigate Epstein-Barr virus (EBV) subtypes in Chinese patients with Hodgkin's disease (HD). METHODS: 113 cases of HD patients with EBV latent membrane protein 1 (LMP-1) and/or EBV encoded small RAN (EBER-1) positive and throat washings from 21 healthy persons were studied for EBV subtypes by polymerase chain reaction (PCR). RESULTS: 68 HD cases exhibited specific bands, in which 62 cases were EBV type A and 6 cases were EBV type B. 13 of the control washing gave rise to specific bands, of which 11 were EBV type A and 2 of EBV type B. CONCLUSION: The results showed that EBV type A is predominant in Chinese HD patients and healthy individuals.
OBJECTIVE: To investigate Epstein-Barr virus (EBV) subtypes in Chinese patients with Hodgkin's disease (HD). METHODS: 113 cases of HDpatients with EBV latent membrane protein 1 (LMP-1) and/or EBV encoded small RAN (EBER-1) positive and throat washings from 21 healthy persons were studied for EBV subtypes by polymerase chain reaction (PCR). RESULTS: 68 HD cases exhibited specific bands, in which 62 cases were EBV type A and 6 cases were EBV type B. 13 of the control washing gave rise to specific bands, of which 11 were EBV type A and 2 of EBV type B. CONCLUSION: The results showed that EBV type A is predominant in Chinese HDpatients and healthy individuals.