Literature DB >> 11243950

Early detection of COPD in a high-risk population using spirometric screening.

J Zieliñski1, M Bednarek.   

Abstract

STUDY
OBJECTIVES: To evaluate the efficacy of mass spirometry use for the detection of airflow obstruction in a high-risk population.
DESIGN: Free spirometry was offered to smokers who were > 39 years of age with a smoking history of > 10 pack-years. Action was preceded by the dissemination of information on the causes and symptoms of COPD in the local mass media.
SETTING: Pulmonary outpatient clinics in 12 large cities of Poland. PARTICIPANTS: Eleven thousand twenty-seven subjects with the following characteristics were screened: mean (+/- SD) age, 51.8 +/- 12.5 years; men, 57%; current or ex-smokers, 80%; and mean smoking history, 26.1 +/- 16.8 pack-years.
INTERVENTIONS: Smoking history, simple spirometry (FVC and FEV(1)), and an antismoking advice.
RESULTS: Spirometric signs of airway obstruction were found in 24.3% of the subjects who were screened. Of those subjects, mild obstruction was found in 9.5%, moderate obstruction was found in 9.6%, and severe obstruction was found in 5.2%. In smokers aged > or = 40 years who had a smoking history of > 10 pack-years, airway obstruction was found in 30.6%. Airway obstruction was present in 8.3% of smokers < 40 years of age who had a smoking history of < 10 pack-years. Of the 2,200 subjects who had never smoked in their lives, airway obstruction was found in 14.4%.
CONCLUSIONS: Mass spirometry in high-risk groups is an effective and easy method for the early detection of COPD.

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Mesh:

Year:  2001        PMID: 11243950     DOI: 10.1378/chest.119.3.731

Source DB:  PubMed          Journal:  Chest        ISSN: 0012-3692            Impact factor:   9.410


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