Literature DB >> 1124316

Nonspecificity in the divalent cation antagonism of dihydrostreptomycin action on Mycobacterium smegmatis.

W H Beggs, F A Andrews.   

Abstract

A divalent cation-dependent antagonism of dihydrostreptomycin action on Mycobacterium smegmatis was demonstrated. However, the nutritionally nonessential cations Sr++ and Ba++ inhibited drug action as effectively as the essential ions Mg++ and Ca++, indicating a high degree of nonspecificity.

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Year:  1975        PMID: 1124316

Source DB:  PubMed          Journal:  Res Commun Chem Pathol Pharmacol        ISSN: 0034-5164


  2 in total

1.  Inhibition of dihydrostreptomycin action on Mycobacterium smegmatis by monovalent and divalent cation salts.

Authors:  W H Beggs; F A Andrews
Journal:  Antimicrob Agents Chemother       Date:  1975-05       Impact factor: 5.191

2.  Inhibition of dihydrostreptomycin binding to Mycobacterium smegmatis by monovalent and divalent cation salts.

Authors:  W H Beggs; F A Andrews
Journal:  Antimicrob Agents Chemother       Date:  1976-03       Impact factor: 5.191

  2 in total

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