Literature DB >> 11242556

Right Ventricular Infarction.

Soo-Teik Lim1, James A. Goldstein.   

Abstract

Right ventricular (RV) ischemia occurs in a substantial proportion of patients with acute inferior myocardial infarction (MI), and may result in severe hemodynamic compromise. This defines a high-risk subset of patients with a mortality rate of 25% to 30%, as opposed to an overall mortality rate of approximately 6% patients with inferior MI without right ventricular infarction (RVI). Early recognition of RV ischemic dysfunction is of great importance in inferior MI with clinical evidence of low cardiac output, because the therapeutic approaches are very different from that for cardiogenic shock resulting predominantly from severe left ventricular (LV) failure. Management of RV ischemic dysfunction includes maintenance of RV preload with volume loading and maintenance of atrioventricular synchrony, inotropic support, and reduction of RV afterload in the setting of LV dysfunction. Reperfusion therapy should be initiated in patients with RV ischemic dysfunction. Though the RV appears to be relatively resistant to infarction and has a remarkable ability to recover even after prolonged occlusion, successful reperfusion of the right coronary artery and major RV branches rapidly improves RV ejection fraction and hemodynamic status, and decreases in-hospital mortality and morbidity.

Entities:  

Year:  2001        PMID: 11242556     DOI: 10.1007/s11936-001-0065-y

Source DB:  PubMed          Journal:  Curr Treat Options Cardiovasc Med        ISSN: 1092-8464


  16 in total

1.  1999 update: ACC/AHA Guidelines for the Management of Patients With Acute Myocardial Infarction: Executive Summary and Recommendations: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction).

Authors:  T J Ryan; E M Antman; N H Brooks; R M Califf; L D Hillis; L F Hiratzka; E Rapaport; B Riegel; R O Russell; E E Smith; W D Weaver; R J Gibbons; J S Alpert; K A Eagle; T J Gardner; A Garson; G Gregoratos; S C Smith
Journal:  Circulation       Date:  1999-08-31       Impact factor: 29.690

2.  Treatment of right ventricular infarction: thrombolytic therapy, coronary angioplasty or neither?

Authors:  R A O'Rourke
Journal:  J Am Coll Cardiol       Date:  1998-10       Impact factor: 24.094

3.  Rapid hemodynamic improvement in right ventricular infarction after coronary angioplasty.

Authors:  A E Moreyra; C Suh; M N Porway; J B Kostis
Journal:  Chest       Date:  1988-07       Impact factor: 9.410

4.  Reversal of atropine-resistant atrioventricular block with intravenous aminophylline in the early phase of inferior wall acute myocardial infarction following treatment with streptokinase.

Authors:  J Goodfellow; P R Walker
Journal:  Eur Heart J       Date:  1995-06       Impact factor: 29.983

5.  Acute right ventricular dilatation in response to ischemia significantly impairs left ventricular systolic performance.

Authors:  C Brookes; H Ravn; P White; U Moeldrup; P Oldershaw; A Redington
Journal:  Circulation       Date:  1999-08-17       Impact factor: 29.690

Review 6.  Right heart ischemia: pathophysiology, natural history, and clinical management.

Authors:  J A Goldstein
Journal:  Prog Cardiovasc Dis       Date:  1998 Jan-Feb       Impact factor: 8.194

7.  Rapid hemodynamic improvement after reperfusion during right ventricular infarction.

Authors:  J W Kinn; S C Ajluni; J G Samyn; E R Bates; C L Grines; W O'Neill
Journal:  J Am Coll Cardiol       Date:  1995-11-01       Impact factor: 24.094

8.  Right atrial ischemia exacerbates hemodynamic compromise associated with experimental right ventricular dysfunction.

Authors:  J A Goldstein; J S Tweddell; B Barzilai; Y Yagi; A S Jaffe; J L Cox
Journal:  J Am Coll Cardiol       Date:  1991-11-15       Impact factor: 24.094

9.  Determinants of the recovery of right ventricular performance following experimental chronic right coronary artery occlusion.

Authors:  S B Laster; T J Shelton; B Barzilai; J A Goldstein
Journal:  Circulation       Date:  1993-08       Impact factor: 29.690

10.  Right ventricular infarction as an independent predictor of prognosis after acute inferior myocardial infarction.

Authors:  M Zehender; W Kasper; E Kauder; M Schönthaler; A Geibel; M Olschewski; H Just
Journal:  N Engl J Med       Date:  1993-04-08       Impact factor: 91.245

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