OBJECTIVE: To evaluate a new minimally invasive surgery for treatment of the polycystic ovary syndrome (PCOS) in clomiphene-resistant infertile women. DESIGN: Prospective study. SETTING: University teaching hospital. PATIENT(S): Thirteen clomiphene citrate-resistant anovulatory women with PCOS. INTERVENTION(S): Operative transvaginal hydrolaparoscopy (THL) using a coaxial bipolar electrode. MAIN OUTCOME MEASURE(S): Feasability, ovulation rate, and pregnancy rate. RESULT(S): Ovarian drilling was performed by THL in all patients; no surgical complications occurred. Mean (+/-SD) duration of follow-up time was 6.3 +/- 3.3 months. Six patients recovered to have regular ovulatory cycles. Six pregnancies occurred; three were spontaneous, two occurred after stimulation and intrauterine insemination, and one occurred after IVF. The cumulative pregnancy rate was 33% at 3 months after THL and 71% at 6 months after THL. No miscarriages occurred. CONCLUSION(S): Transvaginal hydrolaparoscopy with ovarian drilling using bipolar electrosurgery appears to be an alternative minimally invasive in patients with PCOS who are resistant to clomiphene therapy.
OBJECTIVE: To evaluate a new minimally invasive surgery for treatment of the polycystic ovary syndrome (PCOS) in clomiphene-resistant infertile women. DESIGN: Prospective study. SETTING: University teaching hospital. PATIENT(S): Thirteen clomiphene citrate-resistant anovulatory women with PCOS. INTERVENTION(S): Operative transvaginal hydrolaparoscopy (THL) using a coaxial bipolar electrode. MAIN OUTCOME MEASURE(S): Feasability, ovulation rate, and pregnancy rate. RESULT(S): Ovarian drilling was performed by THL in all patients; no surgical complications occurred. Mean (+/-SD) duration of follow-up time was 6.3 +/- 3.3 months. Six patients recovered to have regular ovulatory cycles. Six pregnancies occurred; three were spontaneous, two occurred after stimulation and intrauterine insemination, and one occurred after IVF. The cumulative pregnancy rate was 33% at 3 months after THL and 71% at 6 months after THL. No miscarriages occurred. CONCLUSION(S): Transvaginal hydrolaparoscopy with ovarian drilling using bipolar electrosurgery appears to be an alternative minimally invasive in patients with PCOS who are resistant to clomiphene therapy.
Authors: Marlene Hager; René Wenzl; Sonja Riesenhuber; Julian Marschalek; Lorenz Kuessel; Daniel Mayrhofer; Robin Ristl; Christine Kurz; Johannes Ott Journal: J Clin Med Date: 2019-08-14 Impact factor: 4.241
Authors: Antonio Mercorio; Luigi Della Corte; Maria Chiara De Angelis; Cira Buonfantino; Carlo Ronsini; Giuseppe Bifulco; Pierluigi Giampaolino Journal: Medicina (Kaunas) Date: 2022-07-27 Impact factor: 2.948
Authors: Santiago Horgan; John P Cullen; Mark A Talamini; Yoav Mintz; Alberto Ferreres; Garth R Jacobsen; Bryan Sandler; Julie Bosia; Thomas Savides; David W Easter; Michelle K Savu; Sonia L Ramamoorthy; Emily Whitcomb; Sanjay Agarwal; Emily Lukacz; Guillermo Dominguez; Pedro Ferraina Journal: Surg Endosc Date: 2009-04-03 Impact factor: 4.584