Literature DB >> 11238580

Hepatitis A vaccination during an outbreak among gay men in Montréal, Canada, 1995-1997.

R Allard1, J Beauchemin, L Bédard, R Dion, M Tremblay, J Carsley.   

Abstract

STUDY
OBJECTIVE: To evaluate an intervention designed to curtail an outbreak of hepatitis A among gay men, especially the young and sexually active, by promoting their free vaccination.
DESIGN: The study analysed routine passive surveillance data, carried out questionnaire and serological surveys of vaccinees, and surveys among the target population in non-clinical venues. SETTING AND INTERVENTION: 15 000 free doses of hepatitis A vaccine were made available through clinics with large gay clienteles, or at gay events, and advertised by various means, in Montréal, Canada, from August 1996 to November 1997. Simultaneous vaccination against hepatitis B (always free for gay men) was also encouraged. PARTICIPANTS: Information was obtained from persons with the disease during the epidemic period, a sample of men requesting vaccination, and five community samples of gay men. MAIN
RESULTS: The outbreak involved 376 gay men and the vaccine was distributed to approximately 10 000. Vaccinees were older than cases, but had many sex partners and comprised more food handlers. Special vaccination clinics at gay events were well attended but did not reach more high risk men than regular medical venues. A self reported vaccine coverage of 49% was achieved, but 26% of vaccinees already had anti-HAV antibodies. Disease incidence declined rapidly during the campaign.
CONCLUSIONS: The intervention nearly tripled self reported hepatitis A vaccine coverage but its late start precludes proving that it caused the subsequent drop in incidence. However, it also increased hepatitis B vaccination and it is believed it improved links between gay men, public health, clinicians and community groups.

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Year:  2001        PMID: 11238580      PMCID: PMC1731875          DOI: 10.1136/jech.55.4.251

Source DB:  PubMed          Journal:  J Epidemiol Community Health        ISSN: 0143-005X            Impact factor:   3.710


  19 in total

1.  Outbreak of hepatitis A in homosexual men in Riverside.

Authors:  A Newell; D Asboe; B Azadian
Journal:  Sex Transm Infect       Date:  1998-08       Impact factor: 3.519

2.  Interruption of an outbreak of hepatitis A in two villages by vaccination.

Authors:  V Príkazský; V Oleár; A Cernoch; A Safary; F E André
Journal:  J Med Virol       Date:  1994-12       Impact factor: 2.327

Review 3.  An epidemic of acute viral hepatitis in male homosexuals. Etiology and clinical characteristics.

Authors:  G Høybye; P Skinhøj; B Hentzer; V Faber; L Mathiesen
Journal:  Scand J Infect Dis       Date:  1980

4.  Community wide outbreak of hepatitis A linked to children in day care centres and with increased transmission in young adult men in Florida 1988-9.

Authors:  J C Desenclos; L MacLafferty
Journal:  J Epidemiol Community Health       Date:  1993-08       Impact factor: 3.710

5.  A controlled trial of a formalin-inactivated hepatitis A vaccine in healthy children.

Authors:  A Werzberger; B Mensch; B Kuter; L Brown; J Lewis; R Sitrin; W Miller; D Shouval; B Wiens; G Calandra
Journal:  N Engl J Med       Date:  1992-08-13       Impact factor: 91.245

6.  Testing for antibody to hepatitis A to decrease the cost of hepatitis A prophylaxis with immune globulin or hepatitis A vaccines.

Authors:  J P Bryan; M Nelson
Journal:  Arch Intern Med       Date:  1994-03-28

7.  Sexual transmission of hepatitis A in homosexual men: incidence and mechanism.

Authors:  L Corey; K K Holmes
Journal:  N Engl J Med       Date:  1980-02-21       Impact factor: 91.245

8.  An outbreak of hepatitis A among homosexual men in Melbourne.

Authors:  T Stewart; N Crofts
Journal:  Med J Aust       Date:  1993-04-19       Impact factor: 7.738

9.  Hepatitis A vaccination of men who have sex with men--Atlanta, Georgia, 1996-1997.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  1998-09-04       Impact factor: 17.586

10.  An epidemic outbreak of hepatitis A among homosexual men in Stockholm. Hepatitis A, a special hazard for the male homosexual subpopulation in Sweden.

Authors:  B Christenson; C Broström; M Böttiger; J Hermanson; O Weiland; G Ryd; J V Berg; R Sjöblom
Journal:  Am J Epidemiol       Date:  1982-10       Impact factor: 4.897

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Review 4.  Hepatitis A virus infection and hepatitis A vaccination in human immunodeficiency virus-positive patients: A review.

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Journal:  World J Gastroenterol       Date:  2017-05-28       Impact factor: 5.742

5.  Outbreak of hepatitis A virus infection in Taiwan, June 2015 to September 2017.

Authors:  Wan-Chin Chen; Po-Hsun Chiang; Yu-Hsin Liao; Lin-Ching Huang; Ying-Jung Hsieh; Chu-Ming Chiu; Yi-Chun Lo; Chin-Hui Yang; Jyh-Yuan Yang
Journal:  Euro Surveill       Date:  2019-04

6.  Hepatitis vaccination of men who have sex with men at gay pride events.

Authors:  Erik David Storholm; Dennis G Fisher; Grace L Reynolds; Lucy E Napper; Timothy A Morrisse; Lee M Kochems
Journal:  Prev Sci       Date:  2010-06

7.  Trends of hepatitis A hospitalization and risk factors in Quebec, Canada, between 1990 and 2003.

Authors:  Magalie Canuel; Gaston De Serres; Bernard Duval; Rodica Gilca; Philippe De Wals; Vladimir Gilca
Journal:  BMC Infect Dis       Date:  2007-04-18       Impact factor: 3.090

  7 in total

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