Literature DB >> 11238235

Development of a novel screen for protease inhibitors.

L Gillim1, G L Gusella, J Vargas, D Marras, M E Klotman, A Cara.   

Abstract

We have developed a novel plasmid-based, quantitative, in vitro screen to test the protease-inhibiting activities of existing and newly discovered agents.

Mesh：

Substances：

Year:  2001        PMID： 11238235      PMCID： PMC96076          DOI： 10.1128/CDLI.8.2.437-440.2001

Source DB:  PubMed          Journal:  Clin Diagn Lab Immunol        ISSN： 1071-412X


  9 in total

1.  Use of GFP as a reporter for the facile analysis of sequence-specific proteases.

Authors:  J C Pehrson; A Weatherman; J Markwell; G Sarath; S D Schwartzbach
Journal:  Biotechniques       Date:  1999-07       Impact factor: 1.993

2.  Exploration of the Drosophila acetylcholinesterase substrate activation site using a reversible inhibitor (Triton X-100) and mutated enzymes.

Authors:  V Marcel; S Estrada-Mondaca; F Magné; J Stojan; A Klaébé; D Fournier
Journal:  J Biol Chem       Date:  2000-04-21       Impact factor: 5.157

3.  Epitope-based assay to determine the efficiency of cleavage by HIV-1 protease.

Authors:  D Serio; I T Weber; R W Harrison; J M Louis; A Srinivasan
Journal:  Biotechniques       Date:  1999-02       Impact factor: 1.993

4.  Dual effects of anti-inflammatory 2-arylpropionic acid derivatives on a major isoform of human liver 3alpha-hydroxysteroid dehydrogenase.

Authors:  T Yamamoto; K Matsuura; S Shintani; A Hara; Y Miyabe; T Sugiyama; Y Katagiri
Journal:  Biol Pharm Bull       Date:  1998-11       Impact factor: 2.233

Review 5.  Viral proteases: evolution of diverse structural motifs to optimize function.

Authors:  L M Babé; C S Craik
Journal:  Cell       Date:  1997-11-14       Impact factor: 41.582

6.  Potent inhibition of human immunodeficiency virus type 1 (HIV-1) replication by inducible expression of HIV-1 PR multimers.

Authors:  S J Arrigo; K Huffman
Journal:  J Virol       Date:  1995-10       Impact factor: 5.103

7.  Human serum attenuates the activity of protease inhibitors toward wild-type and mutant human immunodeficiency virus.

Authors:  A Molla; S Vasavanonda; G Kumar; H L Sham; M Johnson; B Grabowski; J F Denissen; W Kohlbrenner; J J Plattner; J M Leonard; D W Norbeck; D J Kempf
Journal:  Virology       Date:  1998-10-25       Impact factor: 3.616

8.  An Escherichia coli expression assay and screen for human immunodeficiency virus protease variants with decreased susceptibility to indinavir.

Authors:  L Melnick; S S Yang; R Rossi; C Zepp; D Heefner
Journal:  Antimicrob Agents Chemother       Date:  1998-12       Impact factor: 5.191

9.  Development of in vitro peptide substrates for human rhinovirus-14 2A protease.

Authors:  Q M Wang; R B Johnson; W Sommergruber; T A Shepherd
Journal:  Arch Biochem Biophys       Date:  1998-08-01       Impact factor: 4.013
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.