Literature DB >> 11238234

Duration of sample storage dramatically alters expression of the human immunodeficiency virus coreceptors CXCR4 and CCR5.

S Shalekoff1, C T Tiemessen.   

Abstract

Expression of the chemokine receptors CXCR4 and CCR5 was monitored using EDTA-anticoagulated whole blood held for different time periods prior to fluorescent-antibody staining. When left overnight CXCR4 expression on leukocytes was substantially increased, whereas CCR5 expression was reduced. The results were similar when heparin and acid-citrate-dextrose were used as anticoagulants.

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Year:  2001        PMID: 11238234      PMCID: PMC96075          DOI: 10.1128/CDLI.8.2.432-436.2001

Source DB:  PubMed          Journal:  Clin Diagn Lab Immunol        ISSN: 1071-412X


  13 in total

1.  Thalidomide suppresses Up-regulation of human immunodeficiency virus coreceptors CXCR4 and CCR5 on CD4+ T cells in humans.

Authors:  N P Juffermans; A Verbon; D P Olszyna; S J van Deventer; P Speelman; T van Der Poll
Journal:  J Infect Dis       Date:  2000-05-15       Impact factor: 5.226

2.  Activation of blood T lymphocytes down-regulates CXCR4 expression and interferes with propagation of X4 HIV strains.

Authors:  M Bermejo; J Martín-Serrano; E Oberlin; M A Pedraza; A Serrano; B Santiago; A Caruz; P Loetscher; M Baggiolini; F Arenzana-Seisdedos; J Alcami
Journal:  Eur J Immunol       Date:  1998-10       Impact factor: 5.532

3.  Identification of a major co-receptor for primary isolates of HIV-1.

Authors:  H Deng; R Liu; W Ellmeier; S Choe; D Unutmaz; M Burkhart; P Di Marzio; S Marmon; R E Sutton; C M Hill; C B Davis; S C Peiper; T J Schall; D R Littman; N R Landau
Journal:  Nature       Date:  1996-06-20       Impact factor: 49.962

4.  The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes.

Authors:  C C Bleul; L Wu; J A Hoxie; T A Springer; C R Mackay
Journal:  Proc Natl Acad Sci U S A       Date:  1997-03-04       Impact factor: 11.205

5.  CCR5 and CXCR4 chemokine receptor expression and beta-chemokine production during early T cell repopulation induced by highly active anti-retroviral therapy.

Authors:  A Giovannetti; F Ensoli; F Mazzetta; M De Cristofaro; M Pierdominici; D S Muratori; V Fiorelli; F Aiuti
Journal:  Clin Exp Immunol       Date:  1999-10       Impact factor: 4.330

6.  HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor.

Authors:  Y Feng; C C Broder; P E Kennedy; E A Berger
Journal:  Science       Date:  1996-05-10       Impact factor: 47.728

7.  CD4+ T cell surface CCR5 density as a determining factor of virus load in persons infected with human immunodeficiency virus type 1.

Authors:  J Reynes; P Portales; M Segondy; V Baillat; P André; B Réant; O Avinens; G Couderc; M Benkirane; J Clot; J F Eliaou; P Corbeau
Journal:  J Infect Dis       Date:  2000-03       Impact factor: 5.226

8.  Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells.

Authors:  F Cocchi; A L DeVico; A Garzino-Demo; S K Arya; R C Gallo; P Lusso
Journal:  Science       Date:  1995-12-15       Impact factor: 47.728

9.  HIV coreceptor downregulation as antiviral principle: SDF-1alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication.

Authors:  A Amara; S L Gall; O Schwartz; J Salamero; M Montes; P Loetscher; M Baggiolini; J L Virelizier; F Arenzana-Seisdedos
Journal:  J Exp Med       Date:  1997-07-07       Impact factor: 14.307

10.  Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4.

Authors:  N Signoret; J Oldridge; A Pelchen-Matthews; P J Klasse; T Tran; L F Brass; M M Rosenkilde; T W Schwartz; W Holmes; W Dallas; M A Luther; T N Wells; J A Hoxie; M Marsh
Journal:  J Cell Biol       Date:  1997-11-03       Impact factor: 10.539

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  5 in total

1.  Age-related changes in expression of CXCR4 and CCR5 on peripheral blood leukocytes from uninfected infants born to human immunodeficiency virus type 1-infected mothers.

Authors:  Sharon Shalekoff; Glenda E Gray; Caroline T Tiemessen
Journal:  Clin Diagn Lab Immunol       Date:  2004-01

2.  Marked differences in CCR5 expression and activation levels in two South African populations.

Authors:  Anabela C P Picton; Sharon Shalekoff; Maria Paximadis; Caroline T Tiemessen
Journal:  Immunology       Date:  2012-08       Impact factor: 7.397

3.  Differences in T cell distribution and CCR5 expression in HIV-positive and HIV-exposed seronegative persons who inject drugs.

Authors:  Eveli Kallas; Kristi Huik; Silver Türk; Merit Pauskar; Ene-Ly Jõgeda; Marina Šunina; Tõnis Karki; Don Des Jarlais; Anneli Uusküla; Radko Avi; Irja Lutsar
Journal:  Med Microbiol Immunol       Date:  2015-12-22       Impact factor: 3.402

4.  Reduced CD4 T cell activation and in vitro susceptibility to HIV-1 infection in exposed uninfected Central Africans.

Authors:  Evélyne Bégaud; Loïc Chartier; Valéry Marechal; Julienne Ipero; Josianne Léal; Pierre Versmisse; Guillaume Breton; Arnaud Fontanet; Corinne Capoulade-Metay; Hervé Fleury; Françoise Barré-Sinoussi; Daniel Scott-Algara; Gianfranco Pancino
Journal:  Retrovirology       Date:  2006-06-22       Impact factor: 4.602

5.  Unbiased transcriptomes of resting human CD4⁺ CD45RO⁺ T lymphocytes.

Authors:  Kerstin Westendorf; Anna Okhrimenko; Joachim R Grün; Heidi Schliemann; Hyun-Dong Chang; Jun Dong; Andreas Radbruch
Journal:  Eur J Immunol       Date:  2014-04-16       Impact factor: 5.532

  5 in total

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