| Literature DB >> 11237264 |
M Bragadin1, D Marton, S Manente, A Toninello.
Abstract
The interactions of tributyllead with lysosomes from rat liver have been studied. It results that the organometal compound induces a fast alkalinization in energized lysosomes. The interpretation is that the compound is a potent proton carrier. This function could explain the toxicity, in particular at neurological level of the compound.Entities:
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Year: 2001 PMID： 11237264 DOI： 10.1016/s0162-0134(00)00195-1
Source DB: PubMed Journal: J Inorg Biochem ISSN： 0162-0134 Impact factor: 4.155