Literature DB >> 11235812

Monoamine oxidase B inhibitors from the fruits of Opuntia ficus-indica var. saboten.

Y N Han1, Y Choo, Y C Lee, Y I Moon, S D Kim, J W Choi.   

Abstract

Three varieties of methyl citrate and 1-methyl malate were isolated from the fruits of Opuntia ficus-indica var. saboten Makino through in vitro bioassay-guided isolation for the inhibition on monoamine oxidase(MAO). The IC50 values for MAO-B of 1-monomethyl citrate, 1,3-dimethyl citrate, trimethyl citrate and 1-methyl malate were 0.19, 0.23, 0.61 and 0.25 mM, respectively. However, on MAO-A, their inhibitions showed only marginal activity.

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Year:  2001        PMID: 11235812     DOI: 10.1007/bf02976493

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN: 0253-6269            Impact factor:   4.946


  4 in total

1.  Bioassay-Guided Isolation of Antioxidant and Cytoprotective Constituents from a Maqui Berry (Aristotelia chilensis) Dietary Supplement Ingredient As Markers for Qualitative and Quantitative Analysis.

Authors:  Jie Li; Chunhua Yuan; Li Pan; P Annécie Benatrehina; Heebyung Chai; William J Keller; C Benjamin Naman; A Douglas Kinghorn
Journal:  J Agric Food Chem       Date:  2017-09-26       Impact factor: 5.279

Review 2.  Selective MAO-B inhibitors: a lesson from natural products.

Authors:  Simone Carradori; Melissa D'Ascenzio; Paola Chimenti; Daniela Secci; Adriana Bolasco
Journal:  Mol Divers       Date:  2013-11-12       Impact factor: 2.943

3.  Monoamine Oxidase and Dopamine β-Hydroxylase Inhibitors from the Fruits of Gardenia jasminoides.

Authors:  Ji Ho Kim; Gun Hee Kim; Keum Hee Hwang
Journal:  Biomol Ther (Seoul)       Date:  2012-03       Impact factor: 4.634

4.  Xanthoangelol and 4-Hydroxyderricin Are the Major Active Principles of the Inhibitory Activities against Monoamine Oxidases on Angelica keiskei K.

Authors:  Ji Ho Kim; Yeon Kyung Son; Gun Hee Kim; Keum Hee Hwang
Journal:  Biomol Ther (Seoul)       Date:  2013-05-30       Impact factor: 4.634

  4 in total

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