| Literature DB >> 11229771 |
Y G Suh1, Y H Kim, M H Park, Y H Choi, H K Lee, J Y Moon, K H Min, D Y Shin, J K Jung, O H Park, R O Jeon, H S Park, S A Kang.
Abstract
The structure-activity relationship and molecular modelings of a novel pimarane COX-2 inhibitor are reported. Particularly, a series of linker extended analogues designed on the basis of these studies exhibited significantly enhanced COX-2 inhibitory activities and selectivities.Entities:
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Year: 2001 PMID： 11229771 DOI： 10.1016/s0960-894x(01)00004-x
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823