Literature DB >> 11229743

Photochemical N-demethylation of alkaloids.

J A Ripper1, E R Tiekink, P J Scammells.   

Abstract

Certain alkaloids were observed to undergo N-demethylation processes under photochemical conditions. Tropine, acetyltropine, tropinone, and atropine were cleanly N-demethylated upon treatment with tetraphenylporphin, oxygen, and light. Dextromethorphan also underwent a N-demethylation reaction, but reacted further to afford an imine. In contrast, 14-acyloxycodeinones underwent a photochemically induced tandem N-demethylation acyl migration.

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Year:  2001        PMID： 11229743     DOI： 10.1016/s0960-894x(00)00690-9

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  3 in total

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3.  Organophotocatalytic N-Demethylation of Oxycodone Using Molecular Oxygen.

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Journal:  Chemistry       Date:  2020-02-18       Impact factor: 5.236
  3 in total

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