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Literature DB >> 11229600

Focal adhesions: structure and dynamics.

Abstract

Interactions of cells with the extracellular matrix are essential for the control of tissue remodelling, cell migration, and embryogenesis. At the cell-extracellular matrix contact points, specialized structures are formed and termed focal adhesions, where transmembrane adhesion receptors provide a structural link between the actin cytoskeleton and the extracellular matrix components. Numerous structural and regulatory proteins assemble at the cytoplasmic face of focal adhesions in a Rho-dependent fashion.

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Year: 2000 PMID： 11229600 DOI： 10.1016/s0248-4900(00)01101-1

Source DB: PubMed Journal: Biol Cell ISSN： 0248-4900 Impact factor: 4.458

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Cited

91 in total

1. MEKK1 regulates calpain-dependent proteolysis of focal adhesion proteins for rear-end detachment of migrating fibroblasts.

Authors: Bruce D Cuevas; Amy N Abell; James A Witowsky; Toshiaki Yujiri; Nancy Lassignal Johnson; Kamala Kesavan; Marti Ware; Peter L Jones; Scott A Weed; Roberta L DeBiasi; Yoshitomo Oka; Kenneth L Tyler; Gary L Johnson
Journal: EMBO J Date: 2003-07-01 Impact factor: 11.598

10. The G protein-coupled estrogen receptor-1, GPER-1, promotes fibrillogenesis via a Shc-dependent pathway resulting in anchorage-independent growth.

Authors: Hilary T Magruder; Jeffrey A Quinn; Jean E Schwartzbauer; Jonathan Reichner; Allan Huang; Edward J Filardo
Journal: Horm Cancer Date: 2014-08-06 Impact factor: 3.869

Focal adhesions: structure and dynamics.

1. MEKK1 regulates calpain-dependent proteolysis of focal adhesion proteins for rear-end detachment of migrating fibroblasts.

2. Th2 cytokines IL-4 and IL-13 downregulate paxillin expression in bronchial airway epithelial cells.

3. Proteomic study of calpeptin-induced differentiation on calpain-interacting proteins of C2C12 myoblast.

4. Dissecting the molecular architecture of integrin adhesion sites by cryo-electron tomography.

5. Dynamics of beta1-integrins in living fibroblasts--effect of substratum wettability.

6. Two LIM domain proteins and UNC-96 link UNC-97/pinch to myosin thick filaments in Caenorhabditis elegans muscle.

7. Separate enrichment analysis of pathways for up- and downregulated genes.

8. Mechanically induced osteogenic differentiation--the role of RhoA, ROCKII and cytoskeletal dynamics.

9. Rab5 activation as a tumor cell migration switch.

10. The G protein-coupled estrogen receptor-1, GPER-1, promotes fibrillogenesis via a Shc-dependent pathway resulting in anchorage-independent growth.