Literature DB >> 11228306

Ocular deposition of copper associated with multiple myeloma.

A S Hawkins1, R M Stein, B I Gaines, T A Deutsch.   

Abstract

PURPOSE: To report a case of hypercupremia with deposits in both eyes on the Descemet's membrane, surface of the iris, and lens capsule associated with multiple myeloma.
METHOD: Case report.
RESULTS: A 64-year-old white woman had metallic deposits in both eyes on the central Descemet's membrane, surface of the iris, and the anterior and posterior lens capsule. A systemic examination revealed an elevated serum copper, normal serum ceruloplasmin, and an increased level of total protein and IgG kappa gammaglobulin. Based on these results, she was diagnosed with multiple myeloma.
CONCLUSIONS: Copper deposits on the Descemet's membrane, surface of the iris, and lens capsule may be the first sign of multiple myeloma.

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Year:  2001        PMID: 11228306     DOI: 10.1016/s0002-9394(00)00657-7

Source DB:  PubMed          Journal:  Am J Ophthalmol        ISSN: 0002-9394            Impact factor:   5.258


  4 in total

1.  Ophthalmic manifestations of atypical IgD multiple myeloma.

Authors:  Matthew R Edmunds; Peter Cikatricis; Subhanjan Mukherji; Jeremy D Bowyer
Journal:  BMJ Case Rep       Date:  2012-07-19

Review 2.  Intraocular collision tumour: case report and literature review.

Authors:  Sarah E Coupland; Andrew Dodson; Hongxiang Liu; Ming-Qing Du; Martina Angi; Bertil E Damato
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2012-12-12       Impact factor: 3.117

3.  The Hematologic Definition of Monoclonal Gammopathy of Undetermined Significance in Relation to Paraproteinemic Keratopathy (An American Ophthalmological Society Thesis).

Authors:  Walter Lisch; Joanna Wasielica-Poslednik; Tero Kivelä; Ursula Schlötzer-Schrehardt; Jens M Rohrbach; Walter Sekundo; Uwe Pleyer; Christina Lisch; Alexander Desuki; Heidi Rossmann; Jayne S Weiss
Journal:  Trans Am Ophthalmol Soc       Date:  2016-08

Review 4.  Hidden in the Eyes-Recurrence of Systemic Hemopathies Reportedly "In Remission": Six Cases and Review of Literature.

Authors:  Margot Denier; Sarah Tick; Romain Dubois; Remy Dulery; Andrew W Eller; Felipe Suarez; Barbara Burroni; Claude-Alain Maurage; Claire Bories; Johanna Konopacki; Michel Puech; Didier Bouscary; Alberte Cantalloube; Emmanuel Héron; Ambroise Marçais; Christophe Habas; Vincent Theillac; Chafik Keilani; Gabrielle R Bonhomme; Denise S Gallagher; Julien Boumendil; Wajed Abarah; Neila Sedira; Stéphane Bertin; Sylvain Choquet; José-Alain Sahel; Lilia Merabet; Françoise Brignole-Baudouin; Marc Putterman; Marie-Hélène Errera
Journal:  Medicina (Kaunas)       Date:  2022-03-21       Impact factor: 2.430

  4 in total

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