| Literature DB >> 11228012 |
Abstract
Immune-dependent growth and development of infectious agents and pathogenesis of disease are increasingly being recognized. It is proposed that the development of filarial larvae to adult stage parasites takes place in an ambiance of inflammatory T helper cell type 1 cytokines in mammalian hosts, and that susceptibility to filarial infections could be governed by the status of macrophage-derived nitric oxide and host ability to produce antibodies to filarial T-independent (carbohydrate) antigens.Entities:
Mesh:
Year: 2001 PMID: 11228012 DOI: 10.1016/s1471-4922(00)01835-3
Source DB: PubMed Journal: Trends Parasitol ISSN: 1471-4922