Literature DB >> 11226587

Were protein internal repeats formed by "bricolage"?

G Lavorgna1, L Patthy, E Boncinelli.   

Abstract

Is evolution an engineer, or is it a tinkerer--a "bricoleur"--building up complex molecules in organisms by increasing and adapting the materials at hand? An analysis of completely sequenced genomes suggests the latter, showing that increasing repetition of modules within the proteins encoded by these genomes is correlated with increasing complexity of the organism.

Mesh:

Year:  2001        PMID: 11226587     DOI: 10.1016/s0168-9525(00)02207-1

Source DB:  PubMed          Journal:  Trends Genet        ISSN: 0168-9525            Impact factor:   11.639


  3 in total

1.  Expansion of protein domain repeats.

Authors:  Asa K Björklund; Diana Ekman; Arne Elofsson
Journal:  PLoS Comput Biol       Date:  2006-07-14       Impact factor: 4.475

2.  Between Interactions and Aggregates: The PolyQ Balance.

Authors:  Pablo Mier; Miguel A Andrade-Navarro
Journal:  Genome Biol Evol       Date:  2021-11-05       Impact factor: 3.416

3.  A New Census of Protein Tandem Repeats and Their Relationship with Intrinsic Disorder.

Authors:  Matteo Delucchi; Elke Schaper; Oxana Sachenkova; Arne Elofsson; Maria Anisimova
Journal:  Genes (Basel)       Date:  2020-04-09       Impact factor: 4.096

  3 in total

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