Literature DB >> 11226235

Mammalian inositol polyphosphate multikinase synthesizes inositol 1,4,5-trisphosphate and an inositol pyrophosphate.

A Saiardi1, E Nagata, H R Luo, A Sawa, X Luo, A M Snowman, S H Snyder.   

Abstract

Using a consensus sequence in inositol phosphate kinase, we have identified and cloned a 44-kDa mammalian inositol phosphate kinase with broader catalytic capacities than any other member of the family and which we designate mammalian inositol phosphate multikinase (mIPMK). By phosphorylating inositol 4,5-bisphosphate, mIPMK provides an alternative biosynthesis for inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)]. mIPMK also can form the pyrophosphate disphosphoinositol tetrakisphosphate (PP-InsP(4)) from InsP(5). Additionally, mIPMK forms InsP(4) from Ins(1,4,5)P(3) and InsP(5) from Ins(1,3,4,5)P(4).

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Year:  2001        PMID： 11226235      PMCID： PMC30134          DOI： 10.1073/pnas.041614598

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  31 in total

1.  Signal transduction. The calcium entry pas de deux.

Authors:  M J Berridge; P Lipp; M D Bootman
Journal:  Science       Date:  2000-03-03       Impact factor: 47.728

2.  Inositol polyphosphate kinase activity of Arg82/ArgRIII is not required for the regulation of the arginine metabolism in yeast.

Authors:  E Dubois; V Dewaste; C Erneux; F Messenguy
Journal:  FEBS Lett       Date:  2000-12-15       Impact factor: 4.124

3.  Basic local alignment search tool.

Authors:  S F Altschul; W Gish; W Miller; E W Myers; D J Lipman
Journal:  J Mol Biol       Date:  1990-10-05       Impact factor: 5.469

4.  The inositol hexakisphosphate kinase family. Catalytic flexibility and function in yeast vacuole biogenesis.

Authors:  A Saiardi; J J Caffrey; S H Snyder; S B Shears
Journal:  J Biol Chem       Date:  2000-08-11       Impact factor: 5.157

5.  Molecular cloning and expression of a complementary DNA for inositol 1,4,5-trisphosphate 3-kinase.

Authors:  K Y Choi; H K Kim; S Y Lee; K H Moon; S S Sim; J W Kim; H K Chung; S G Rhee
Journal:  Science       Date:  1990-04-06       Impact factor: 47.728

6.  Characterization of two genes, ARGRI and ARGRIII required for specific regulation of arginine metabolism in yeast.

Authors:  E Dubois; J Bercy; F Messenguy
Journal:  Mol Gen Genet       Date:  1987-04

7.  Actions of inositol phosphates on Ca2+ pools in guinea-pig hepatocytes.

Authors:  G M Burgess; R F Irvine; M J Berridge; J S McKinney; J W Putney
Journal:  Biochem J       Date:  1984-12-15       Impact factor: 3.857

8.  The pathway of myo-inositol 1,3,4-trisphosphate phosphorylation in liver. Identification of myo-inositol 1,3,4-trisphosphate 6-kinase, myo-inositol 1,3,4-trisphosphate 5-kinase, and myo-inositol 1,3,4,6-tetrakisphosphate 5-kinase.

Authors:  S B Shears
Journal:  J Biol Chem       Date:  1989-11-25       Impact factor: 5.157

9.  Cloning and expression of a cDNA encoding human inositol 1,4,5-trisphosphate 3-kinase C.

Authors:  V Dewaste; V Pouillon; C Moreau; S Shears; K Takazawa; C Erneux
Journal:  Biochem J       Date:  2000-12-01       Impact factor: 3.857

10.  Evidence for lithium-sensitive inositol 4,5-bisphosphate accumulation in muscarinic cholinoceptor-stimulated cerebral-cortex slices.

Authors:  S Jenkinson; R A Challiss; S R Nahorski
Journal:  Biochem J       Date:  1992-10-15       Impact factor: 3.857
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  38 in total

Review 1.  How versatile are inositol phosphate kinases?

Authors:  Stephen B Shears
Journal:  Biochem J       Date:  2004-01-15       Impact factor: 3.857

Review 2.  Defining signal transduction by inositol phosphates.

Authors:  Stephen B Shears; Sindura B Ganapathi; Nikhil A Gokhale; Tobias M H Schenk; Huanchen Wang; Jeremy D Weaver; Angelika Zaremba; Yixing Zhou
Journal:  Subcell Biochem       Date:  2012

Review 3.  Regulation of immune cell development through soluble inositol-1,3,4,5-tetrakisphosphate.

Authors:  Karsten Sauer; Michael P Cooke
Journal:  Nat Rev Immunol       Date:  2010-04       Impact factor: 53.106

Review 4.  Roles for inositol polyphosphate kinases in the regulation of nuclear processes and developmental biology.

Authors:  Andrew M Seeds; Joshua P Frederick; Marco M K Tsui; John D York
Journal:  Adv Enzyme Regul       Date:  2007-01-05

5.  Inositol polyphosphate multikinase is a physiologic PI3-kinase that activates Akt/PKB.

Authors:  David Maag; Micah J Maxwell; Douglas A Hardesty; Katie L Boucher; Namrata Choudhari; Adam G Hanno; Jenny F Ma; Adele S Snowman; Joseph W Pietropaoli; Risheng Xu; Phillip B Storm; Adolfo Saiardi; Solomon H Snyder; Adam C Resnick
Journal:  Proc Natl Acad Sci U S A       Date:  2011-01-10       Impact factor: 11.205

Review 6.  Control of mammalian gene expression by selective mRNA export.

Authors:  Vihandha O Wickramasinghe; Ronald A Laskey
Journal:  Nat Rev Mol Cell Biol       Date:  2015-06-17       Impact factor: 94.444

Review 7.  Conservation of PHO pathway in ascomycetes and the role of Pho84.

Authors:  Parul Tomar; Himanshu Sinha
Journal:  J Biosci       Date:  2014-06       Impact factor: 1.826

8.  Inositol polyphosphate multikinase is a transcriptional coactivator required for immediate early gene induction.

Authors:  Risheng Xu; Bindu D Paul; Dani R Smith; Richa Tyagi; Feng Rao; A Basit Khan; Daniel J Blech; M Scott Vandiver; Maged M Harraz; Prasun Guha; Ishrat Ahmed; Nilkantha Sen; Michela Gallagher; Solomon H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  2013-09-16       Impact factor: 11.205

9.  Inositol Hexakisphosphate Kinase 1 (IP6K1) Regulates Inositol Synthesis in Mammalian Cells.

Authors:  Wenxi Yu; Cunqi Ye; Miriam L Greenberg
Journal:  J Biol Chem       Date:  2016-03-07       Impact factor: 5.157

Review 10.  Inositol pyrophosphates: structure, enzymology and function.

Authors:  Christopher John Barker; Christopher Illies; Gian Carlo Gaboardi; Per-Olof Berggren
Journal:  Cell Mol Life Sci       Date:  2009-08-28       Impact factor: 9.261
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