Literature DB >> 11225749

Variations in plasma soluble tumour necrosis factor receptors after diet-induced weight loss in obesity.

J P Bastard1, C Jardel, E Bruckert, H Vidal, B Hainque.   

Abstract

The aim of this study was to investigate the variations in the plasma levels of the soluble tumour necrosis factor receptor type-I (sTNFR-I) and type-II (sTNFR-II) during weight loss which was induced by 3 weeks on a very low calorie diet (3.9+/-0.1 MJ/day), in 17 non-diabetic obese women. Plasma sTNFR-I concentrations decreased significantly after weight loss (p < 0.05), but there was no significant change in plasma sTNFR-II. As the diet was associated with a significant decrease in body fat mass (=2.5 kg), this result supports the emerging concept that adipose tissue can produce significant amounts of sTNFR-I and that this production can be modified by weight loss in human obesity.

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Year:  2000        PMID: 11225749     DOI: 10.1046/j.1463-1326.2000.00090.x

Source DB:  PubMed          Journal:  Diabetes Obes Metab        ISSN: 1462-8902            Impact factor:   6.577


  17 in total

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Review 8.  Behavioural treatments for chronic systemic inflammation: effects of dietary weight loss and exercise training.

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9.  Markers of inflammation and fat distribution following weight loss in African-American and white women.

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