Literature DB >> 11225459

[Effectiveness of an improved antiseptic in treatment of contaminated soft tissue wounds].

K P Schmit-Neuerburg1, C Bettag, W Schlickewei, W Fabry, J Hanke, K Renzing-Köhler, H Hirche, H J Kock.   

Abstract

A novel antiseptic biguanide has been shown to be more bactericidal and tissue compatible in vitro than other antiseptics. In our controlled, prospective and randomized double-blind study on patients with bacteria-contaminated wound types 2-4, one group (n = 45) was treated with humid cotton swab dressings of 0.2% Lavasept solution compared with Ringer solution (n = 35). No deterioration of wound healing was observed in either group. Lavasept treatment resulted in faster and significant reduction of gram-positive germs. The tissue compatibility of Lavasept was evaluated as significantly better than Ringer solution.

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Year:  2001        PMID: 11225459     DOI: 10.1007/s001040051269

Source DB:  PubMed          Journal:  Chirurg        ISSN: 0009-4722            Impact factor:   0.955


  6 in total

1.  Wounds - from physiology to wound dressing.

Authors:  Peter Kujath; Angela Michelsen
Journal:  Dtsch Arztebl Int       Date:  2008-03-28       Impact factor: 5.594

2.  Intraperitoneal instillation of polihexanide produces hypotension and vasodilation: in vivo and in vitro study in rats.

Authors:  Helge Frieling; Matthias Gründling; Kai-Steffen Lauer; Michael Wendt; Thomas Hachenberg; Thomas Hackenberg; Christian Lehmann; Dragan Pavlovic
Journal:  Int J Colorectal Dis       Date:  2005-10-26       Impact factor: 2.571

3.  [Lavasept as an alternative to PVP-iodine as a preoperative antiseptic in ophthalmic surgery. Randomized, controlled, prospective double-blind trial].

Authors:  F Hansmann; A Kramer; H Ohgke; H Strobel; M Müller; G Geerling
Journal:  Ophthalmologe       Date:  2005-11       Impact factor: 1.059

4.  [Polyhexamethylbiguanid (PHMB) as preoperative antiseptic for cataract surgery].

Authors:  F Hansmann; A Kramer; H Ohgke; H Strobel; M Müller; G Geerling
Journal:  Ophthalmologe       Date:  2004-04       Impact factor: 1.059

5.  In-vitro analysis of the effect of gentamicin and polyhexanide on bone tissue.

Authors:  Hans-Jürgen Kock; Dirk Ernst; Frank Jethon; Werner Fabry
Journal:  Int Orthop       Date:  2013-01-26       Impact factor: 3.075

6.  Peritoneal instillation of taurolidine or polihexanide modulates intestinal microcirculation in experimental endotoxemia.

Authors:  Helge Frieling; Kai-Steffen Lauer; Matthias Gründling; Taras Usichenko; Konrad Meissner; Theoni Kanellopoulou; Christian Lehmann; Michael Wendt; Dragan Pavlovic
Journal:  Int J Colorectal Dis       Date:  2006-11-21       Impact factor: 2.796

  6 in total

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