Literature DB >> 11224726

beta(2)-Adrenergic receptor polymorphisms and asthma.

L Joos1, P D Paré, A J Sandford.   

Abstract

The idea that an abnormality in the beta(2)-adrenergic receptor contributes to asthma has been a long-standing hypothesis. Since the discovery of functionally relevant polymorphisms in the beta(2)-adrenergic receptor gene, there has been intensive research on their impact on asthma and related phenotypes, particularly the responsiveness to bronchodilators. It is the aim of this chapter to summarize the latest developments in this interesting field of research.

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Year:  2001        PMID： 11224726     DOI： 10.1097/00063198-200103000-00003

Source DB:  PubMed          Journal:  Curr Opin Pulm Med        ISSN： 1070-5287            Impact factor:   3.155


  3 in total

1.  Analysis of ADRB2 (Arg16Gly) Gene Variant with Susceptibility, Pharmacogenetic Response and Disease Severity in South Indian Asthmatics.

Authors:  Srinivas Bandaru; Jyothy Akka; Vijaya Kumar Marri; Mallika Alvala; Deepika Ponnala; Hema Prasad Mundluru
Journal:  Inflammation       Date:  2015-12       Impact factor: 4.092

2.  Polymorphisms in the beta2 adrenergic receptor and bronchodilator response, bronchial hyperresponsiveness, and rate of decline in lung function in smokers.

Authors:  L Joos; T D Weir; J E Connett; N R Anthonisen; R Woods; P D Paré; A J Sandford
Journal:  Thorax       Date:  2003-08       Impact factor: 9.139

3.  Role of ADRB2 gene polymorphism in asthma and response to beta(2)-agonists in Polish children.

Authors:  A Szczepankiewicz; A Breborowicz; P Sobkowiak; L Kramer; A Popiel
Journal:  J Appl Genet       Date:  2009       Impact factor: 3.240
  3 in total

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