The need for empirically derived permeation data for personal protective equipment: the death of Dr. Karen E. Wetterhahn.

Personal protective equipment (PPE) is an essential component in any occupational health and safety program. The appropriate selection and use of PPE can help prevent or limit exposure to hazardous materials. The inappropriate selection or use of PPE can lead to unnecessary exposure or --with extremely hazardous materials--serious harm including death. In 1997, Dr. Karen E. Wetterhahn died from mercury poisoning resulting from a single exposure to dimethylmercury almost a year before. Her death raised numerous questions as to how this tragedy occurred and what could be done to protect against a chemical as dangerous as dimethylmercury. This article provides a brief review of the case and discusses the glove permeation testing done during the course of the accident investigation. Using this case as an example, the author argues that all recommendations for PPE be based on empirical testing using accepted methods and that this information be readily available.