| Literature DB >> 11214133 |
P Menasché, A A Hagège, M Scorsin, B Pouzet, M Desnos, D Duboc, K Schwartz, J T Vilquin, J P Marolleau.
Abstract
Intramyocardial skeletal muscle transplantation has been shown experimentally to improve heart function after infarction. We report success with this procedure in a patient with severe ischaemic heart failure. We implanted autologous skeletal myoblasts into the postinfarction scar during coronary artery bypass grafting of remote myocardial areas. 5 months later, there was evidence of contraction and viability in the grafted scar on echocardiography and positron emission tomography. Although this result is encouraging, it requires validation by additional studies.Entities:
Mesh：
Year: 2001 PMID： 11214133 DOI： 10.1016/S0140-6736(00)03617-5
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321