Literature DB >> 112123

A monoclonal macroglobulin with antinuclear activity.

L Intrator, C Andre, C Chenal, C Sultan.   

Abstract

Serum containing a monoclonal IgM protein from a patient with Waldenstroms' macroglobulinaemia gave intense immunofluorescent staining of kidney nuclei. The Fab mu fragments of this immunoglobulin were obtained. The IgM and Fab fragments reacted in vitro with kidney nuclei using unfixed cryostat sections of rat or mouse kidney. After treatment of the patient with chemotherapy, the monoclonal IgM disappeared, and no more antinuclear activity could be detected in the serum. The results strongly suggest that this IgM protein had antinuclear activity.

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Year:  1979        PMID： 112123      PMCID： PMC1145706          DOI： 10.1136/jcp.32.5.450

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  19 in total

Review 1.  Antinuclear antibodies.

Authors:  A P Peltier; D Estes
Journal:  Pathobiol Annu       Date:  1972

2.  Antibody activity of human myeloma globulins.

Authors:  M Seligmann; J C Brouet
Journal:  Semin Hematol       Date:  1973-04       Impact factor: 3.851

Review 3.  Myeloma proteins (M-components) with antibody-like activity.

Authors:  M Potter
Journal:  N Engl J Med       Date:  1971-04-15       Impact factor: 91.245

4.  The specificity of a monoclonal macroglobulin (gamma M) antibody: reactivity with primate gamma G immunoglobulins.

Authors:  M J Stone; H Metzger
Journal:  J Immunol       Date:  1969-01       Impact factor: 5.422

5.  Ultrastructural localization and characterization of a ribosomal antibody detected by immunofluorescence in systemic lupus erythematosus.

Authors:  F B Bianchi; M Rizzetto; P Penfold; G T Swana; D Doniach
Journal:  Clin Exp Immunol       Date:  1974-08       Impact factor: 4.330

6.  Ribonucleoprotein (RNP) soluble nuclear antigen: demonstration of its reaction with serum antibodies by counter-immunoelectrophoresis and further partial characterization.

Authors:  A P Peltier; C Aussel; T Haim; L Cyna
Journal:  J Immunol Methods       Date:  1977       Impact factor: 2.303

7.  A human immunoglobulin in myeloma protein with anti-gastric parietal cell autoantigen activity.

Authors:  C Micouin; C Rivat; J C Bensa; P Stoebner; M Favre; E Hudry
Journal:  Clin Exp Immunol       Date:  1977-01       Impact factor: 4.330

8.  An immunofluorescent study of the skin lesions in systemic lupus erythematosus.

Authors:  E M Tan; H G Kunkel
Journal:  Arthritis Rheum       Date:  1966-02

9.  Naturally occurring low molecular weight IgM in patients with rheumatoid arthritis, systemic lupus erythematosus and macroglobulinemia. I. Purification and immunologic studies.

Authors:  V Harisdangkul; J S McDougal; M Knapp; C L Christian
Journal:  J Immunol       Date:  1975-07       Impact factor: 5.422

10.  Papain digestion fragments of human IgM globulins.

Authors:  C Mihaesco; M Seligmann
Journal:  J Exp Med       Date:  1968-03-01       Impact factor: 14.307
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  3 in total

1.  Serum monoclonal antibodies derived from patients with multiple myeloma react with mycobacterial phosphoinositides and nuclear antigens.

Authors:  D Buskila; M Abu-Shakra; H Amital-Teplizki; A R Coates; M Krupp; S Sukenik; Y Shoenfeld
Journal:  Clin Exp Immunol       Date:  1989-06       Impact factor: 4.330

2.  The detection of a common idiotype of anti-DNA antibodies in the sera of patients with monoclonal gammopathies.

Authors:  Y Shoenfeld; O Ben-Yehuda; Y Napartstek; Y Wilner; R Frolichman; A Schattner; G Lavie; H Joshua; J Pinkhas; R C Kennedy
Journal:  J Clin Immunol       Date:  1986-05       Impact factor: 8.317

3.  Characterization of a human monoclonal IgM with antibody activity to dsDNA.

Authors:  J P Fermand; F Danon; J C Brouet
Journal:  Clin Exp Immunol       Date:  1985-02       Impact factor: 4.330
  3 in total

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