Literature DB >> 11212117

Solid-phase synthesis of pyrrolo[2,1-c][1,4]benzodiazepine-5,11-diones.

A Kamal1, G S Reddy, S Raghavan.   

Abstract

The solid-phase synthesis of biologically important pyrrolo[2,1-c][1,4]benzodiazepine-5,11-diones using Wang resin through amide formation and reductive cyclization procedures is described. Further, N10-substituents have been introduced in the final products and these have been cleaved from the solid support in good yields.

Entities:  

Mesh:

Substances:

Year:  2001        PMID: 11212117     DOI: 10.1016/s0960-894x(00)00680-6

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

1.  Efficient solid-phase synthesis of 3-substituted-5-oxo-5H-thiazolo[2,3-b]-quinazoline-8-carboxamides under mild conditions with two diversity positions.

Authors:  Isabelle Bouillon; Viktor Krchnák
Journal:  J Comb Chem       Date:  2007-10-02
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.