Literature DB >> 11212107

Antifungal activity of octyl gallate: structural criteria and mode of action.

I Kubo1, P Xiao, K Fujita.   

Abstract

Octyl gallate (3,4,5-trihydroxybenzoate) was found to possess antifungal activity against Saccharomyces cerevisiae and Zygosaccharomyces bailii, in addition to its potent antioxidant activity. Catechol moiety is essential to elicit this activity. The primary fungicidal activity of octyl gallate comes from its ability to act as a nonionic surface-active agent (surfactant). The length of the alkyl chain is not a major contributor but plays an important role in eliciting the activity.

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Year:  2001        PMID： 11212107     DOI： 10.1016/s0960-894x(00)00656-9

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  14 in total

1.  Protective effect of gallic acid against arsenic-induced anxiety-/depression- like behaviors and memory impairment in male rats.

Authors:  Noreen Samad; Sadia Jabeen; Imran Imran; Iqra Zulfiqar; Kainat Bilal
Journal:  Metab Brain Dis       Date:  2019-05-22       Impact factor: 3.584

2.  Effects of methyl gallate and gallic acid on the production of inflammatory mediators interleukin-6 and interleukin-8 by oral epithelial cells stimulated with Fusobacterium nucleatum.

Authors:  Mi-Sun Kang; Hee-Sook Jang; Jong-Suk Oh; Kyu-Ho Yang; Nam-Ki Choi; Hoi-Soon Lim; Seon-Mi Kim
Journal:  J Microbiol       Date:  2010-02-04       Impact factor: 3.422

3.  Combination therapy with octyl gallate and ferulic acid improves cognition and neurodegeneration in a transgenic mouse model of Alzheimer's disease.

Authors:  Takashi Mori; Naoki Koyama; Jun Tan; Tatsuya Segawa; Masahiro Maeda; Terrence Town
Journal:  J Biol Chem       Date:  2017-05-16       Impact factor: 5.157

4.  Antibacterial activity of alkyl gallates against Xanthomonas citri subsp. citri.

Authors:  I C Silva; L O Regasini; M S Petrônio; D H S Silva; V S Bolzani; J Belasque; L V S Sacramento; H Ferreira
Journal:  J Bacteriol       Date:  2012-10-26       Impact factor: 3.490

5.  Activity of gallic acid and its ester derivatives in Caenorhabditis elegans and zebrafish (Danio rerio) models.

Authors:  Junya de Lacorte Singulani; Liliana Scorzoni; Paulo César Gomes; Ana Carolina Nazaré; Carlos Roberto Polaquini; Luis Octávio Regasini; Ana Marisa Fusco-Almeida; Maria José Soares Mendes-Giannini
Journal:  Future Med Chem       Date:  2017-10-27       Impact factor: 3.808

6.  Chemosensitization as a means to augment commercial antifungal agents.

Authors:  Bruce C Campbell; Kathleen L Chan; Jong H Kim
Journal:  Front Microbiol       Date:  2012-02-29       Impact factor: 5.640

7.  Histopathological Analysis from Gallic Acid Administration on Hippocampal Cell Density, Depression, and Anxiety Related Behaviors in A Trimethyltin Intoxication Model.

Authors:  Marzieh Moghadas; Mohammad Amin Edalatmanesh; Reza Robati
Journal:  Cell J       Date:  2016-01-17       Impact factor: 2.479

8.  Anti-methicillin-resistance Staphylococcus aureus (MRSA) compounds from Bauhinia kockiana Korth. And their mechanism of antibacterial activity.

Authors:  Yik Ling Chew; Adlina Maisarah Mahadi; Kak Ming Wong; Joo Kheng Goh
Journal:  BMC Complement Altern Med       Date:  2018-02-20       Impact factor: 3.659

9.  Phytochemical Analysis and Antimicrobial, Antinociceptive, and Anti-Inflammatory Activities of Two Chemotypes of Pimenta pseudocaryophyllus (Myrtaceae).

Authors:  Joelma Abadia Marciano de Paula; Maria do Rosário Rodrigues Silva; Maysa P Costa; Danielle Guimarães Almeida Diniz; Fabyola A S Sá; Suzana Ferreira Alves; Elson Alves Costa; Roberta Campos Lino; José Realino de Paula
Journal:  Evid Based Complement Alternat Med       Date:  2012-10-02       Impact factor: 2.629

10.  Toxicity and Loss of Mitochondrial Membrane Potential Induced by Alkyl Gallates in Trypanosoma cruzi.

Authors:  Rogério Andréo; Luís Octávio Regasini; Maicon Segalla Petrônio; Bruna Galdorfini Chiari-Andréo; Aline Tansini; Dulce Helena Siqueira Silva; Regina Maria Barretto Cicarelli
Journal:  Int Sch Res Notices       Date:  2015-01-28
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