| Literature DB >> 11212102 |
Y Sasaki1, M Hirabuki, A Ambo, H Ouchi, Y Yamamoto.
Abstract
Four Leu-enkephalin (Enk) analogues containing 2',6'-dimethyphenylalanine (Dmp) in position 4 were prepared and tested for their receptor binding and biological activities. Among the analogues prepared, [2', 6'-dimethyltyrosine, D-Dmp4]Enk was found to be an antagonist toward mu and delta opioid receptors with pA2 values of 6.90 and 5.57, respectively.Entities:
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Year: 2001 PMID： 11212102 DOI： 10.1016/s0960-894x(00)00665-x
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823