| Literature DB >> 11210663 |
A M Farghaly1, F S Soliman, M M el Semary, A F Rostom.
Abstract
As a continuation of an earlier interest in polysubstituted pyrazoles, the synthesis of some derivatives of 1H-pyrazol-4-yl-2-oxo-but-3-enoic acid and ethyl 4-hydroxy-1H-pyrazole-3-carboxylates of potential antimicrobial and antiinflammatory activity is described. One compound showed in vitro antibacterial activity and two compounds displayed in vivo antiinflammatory potency in rats.Entities:
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Year: 2001 PMID： 11210663 DOI： 10.1002/chin.200117119
Source DB: PubMed Journal: Pharmazie ISSN： 0031-7144 Impact factor: 1.267