| Literature DB >> 11209133 |
H Takayama1, Y Nagashima, M Hara, H Takagi, M Mori, G Merlino, Y Nakazato.
Abstract
Transgenic mice overexpressing hepatocyte growth factor/scatter factor (HGF/SF) demonstrate extensive pigmented nevi in both skin and leptomeninges of the central nervous system resembling human neurocutaneous melanosis. We immunohistochemically detected HGF/SF receptor, Met, in a congenital nevus of an infant with neurocutaneous melanosis, indicating that deregulation of HGF/SF-Met signaling in the critical period of development may lead to this fatal syndrome.Entities:
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Year: 2001 PMID： 11209133 DOI： 10.1067/mjd.2001.112403
Source DB: PubMed Journal: J Am Acad Dermatol ISSN： 0190-9622 Impact factor: 11.527