Literature DB >> 11207380

Transient receptor potential protein mRNA expression in rat substantia nigra.

J B Sylvester1, J Mwanjewe, A K Grover.   

Abstract

Receptor gated Ca2+ entry has been associated with transient receptor potential (TRP) proteins encoded by several different genes. Here, we compare expression of mRNA for TRP isoforms encoded by genes TRP1-6 in the rat substantia nigra and whole brain. The substantia nigra and the whole brain expressed mRNA predominantly for TRP3 and TRP6. The levels of TRP1, 2, 4 and 5 were very low in both. The TRP6 mRNA levels in substantia nigra and the whole brain were comparable while those for TRP3 were significantly lower in substantia nigra than in the whole brain. Thus substantia nigra differs from the whole brain in its TRP expression.

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Year:  2001        PMID: 11207380     DOI: 10.1016/s0304-3940(01)01533-6

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN: 0304-3940            Impact factor:   3.046


  3 in total

1.  Constitutively active TRPC3 channels regulate basal ganglia output neurons.

Authors:  Fu-Wen Zhou; Shannon G Matta; Fu-Ming Zhou
Journal:  J Neurosci       Date:  2008-01-09       Impact factor: 6.167

2.  Role of transient receptor potential canonical 6 (TRPC6) in non-transferrin-bound iron uptake in neuronal phenotype PC12 cells.

Authors:  James Mwanjewe; Ashok K Grover
Journal:  Biochem J       Date:  2004-03-15       Impact factor: 3.857

3.  TRPC3 and NALCN channels drive pacemaking in substantia nigra dopaminergic neurons.

Authors:  Ki Bum Um; Suyun Hahn; So Woon Kim; Yoon Je Lee; Lutz Birnbaumer; Hyun Jin Kim; Myoung Kyu Park
Journal:  Elife       Date:  2021-08-19       Impact factor: 8.140

  3 in total

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