Literature DB >> 11206462

Synthesis and evaluation of caffeic acid amides as antioxidants.

P Rajan1, I Vedernikova, P Cos, D V Berghe, K Augustyns, A Haemers.   

Abstract

A series of amides of caffeic acid has been synthesised and their antioxidant properties evaluated as lipid peroxidation inhibitors. Anilides of caffeic acid were found to be very efficient antioxidants with IC50's of 0.3 microM.

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Year:  2001        PMID： 11206462     DOI： 10.1016/s0960-894x(00)00630-2

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  17 in total

1.  In silico development, validation and comparison of predictive QSAR models for lipid peroxidation inhibitory activity of cinnamic acid and caffeic acid derivatives using multiple chemometric and cheminformatics tools.

Authors:  Indrani Mitra; Achintya Saha; Kunal Roy
Journal:  J Mol Model       Date:  2012-03-21       Impact factor: 1.810

2.  DFT study of the effect of solvent on the H-atom transfer involved in the scavenging of the free radicals (·)HO2 and (·)O2(-) by caffeic acid phenethyl ester and some of its derivatives.

Authors:  Olivier Holtomo; Mama Nsangou; Jean Jules Fifen; Ousmanou Motapon
Journal:  J Mol Model       Date:  2014-11-13       Impact factor: 1.810

3.  (E)-N-Benzyl-2-cyano-3-phenyl-acryl-amide.

Authors:  Tai-Ran Kang; Lian-Mei Chen
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-12-04

4.  Caffeic acid phenethyl ester and its amide analogue are potent inhibitors of leukotriene biosynthesis in human polymorphonuclear leukocytes.

Authors:  Luc H Boudreau; Jacques Maillet; Luc M LeBlanc; Jacques Jean-François; Mohamed Touaibia; Nicolas Flamand; Marc E Surette
Journal:  PLoS One       Date:  2012-02-09       Impact factor: 3.240

5.  Study on the hypochlolesterolemic and antioxidative effects of tyramine derivatives from the root bark of Lycium chenese Miller.

Authors:  Sung-Hee Cho; Eun-Jung Park; Eun-Ok Kim; Sang-Won Choi
Journal:  Nutr Res Pract       Date:  2011-10-28       Impact factor: 1.926

6.  Neuroprotective and antioxidant effects of novel benzofuran-2-carboxamide derivatives.

Authors:  Jungsook Cho; Chowee Park; Youngmun Lee; Sunyoung Kim; Shambhunath Bose; Minho Choi; Arepalli Sateesh Kumar; Jae-Kyung Jung; Heesoon Lee
Journal:  Biomol Ther (Seoul)       Date:  2015-05-01       Impact factor: 4.634

7.  Targeting matrix metalloproteinases with novel diazepine substituted cinnamic acid derivatives: design, synthesis, in vitro and in silico studies.

Authors:  Dharmender Rathee; Viney Lather; Ajmer Singh Grewal; Harish Dureja
Journal:  Chem Cent J       Date:  2018-04-20       Impact factor: 4.215

8.  New Hybrids Based on Curcumin and Resveratrol: Synthesis, Cytotoxicity and Antiproliferative Activity against Colorectal Cancer Cells.

Authors:  Cristian Hernández; Gustavo Moreno; Angie Herrera-R; Wilson Cardona-G
Journal:  Molecules       Date:  2021-05-01       Impact factor: 4.411

9.  Synthesis of Caffeoyl-Prolyl-Histidyl-Xaa Derivatives and Evaluation of Their Activities and Stability upon Long-Term Storage.

Authors:  Hyeri Jeong; Young-Eun Jeon; Jin-Kyoung Yang; Jaehi Kim; Woo-Jae Chung; Yoon-Sik Lee; Dong-Sik Shin
Journal:  Int J Mol Sci       Date:  2021-06-11       Impact factor: 5.923

10.  Piplartine Analogues and Cytotoxic Evaluation against Glioblastoma.

Authors:  Flávio Rogério da Nóbrega; Ozlem Ozdemir; Sheila Cristina S Nascimento Sousa; Joice Nascimento Barboza; Hasan Turkez; Damião Pergentino de Sousa
Journal:  Molecules       Date:  2018-06-08       Impact factor: 4.411
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