Literature DB >> 11206450

2,2-Dimethyl-4,5-diaryl-3(2H)furanone derivatives as selective cyclo-oxygenase-2 inhibitors.

S S Shin1, M S Noh, Y J Byun, J K Choi, J Y Kim, K M Lim, J Y Ha, J K Kim, C H Lee, S Chung.   

Abstract

A series of 2,2-dimethyl-5-[4-(methylsulfonyl)phenyl]-4-phenyl-3(2H)furanones was prepared and evaluated for their ability to inhibit cyclo-oxygenase-2 (COX-2).

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Year:  2001        PMID: 11206450     DOI: 10.1016/s0960-894x(00)00634-x

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

1.  4,5-Diaryl 3(2H)Furanones: Anti-Inflammatory Activity and Influence on Cancer Growth.

Authors:  Dmitrii Semenok; Jury Medvedev; Lefki-P Giassafaki; Iason Lavdas; Ioannis S Vizirianakis; Phaedra Eleftheriou; Antonis Gavalas; Anthi Petrou; Athina Geronikaki
Journal:  Molecules       Date:  2019-05-06       Impact factor: 4.411

  1 in total

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