| Literature DB >> 11206447 |
N Kaila1, B E Thomas, P Thakker, J C Alvarez, R T Camphausen, D Crommie.
Abstract
The design and synthesis of novel beta-C-mannosides that inhibit the binding of sialyl Lewis x to E-selectin are described. Compounds that contained a phenyl substituent at the C-6 position were found to have increased potency.Entities:
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Year: 2001 PMID: 11206447 DOI: 10.1016/s0960-894x(00)00623-5
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823